Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy
The synthesis, characterization, and applications of iron oxide nanorods have received attention in recent years. Even though there are several studies on the biological applications of iron oxide nanoparticles, recent studies have shown that rod-shaped iron oxides are effective in magnetic hyperthe...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2021-12-01
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| Series: | Nanotechnology Reviews |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/ntrev-2022-0011 |
| _version_ | 1818027262570659840 |
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| author | Mona Lijo P. Songca Sandile P. Ajibade Peter A. |
| author_facet | Mona Lijo P. Songca Sandile P. Ajibade Peter A. |
| author_sort | Mona Lijo P. |
| collection | DOAJ |
| description | The synthesis, characterization, and applications of iron oxide nanorods have received attention in recent years. Even though there are several studies on the biological applications of iron oxide nanoparticles, recent studies have shown that rod-shaped iron oxides are effective in magnetic hyperthermia (MHT) as therapeutic technique to treat cancer. This review focused on the synthesis and encapsulation of magnetic iron oxide nanorods (MIONRs) and their use in (MHT) and photothermal therapy (PTT) for cancer cells. Among the synthetic methods that have been used to prepare MIONRs, some could be used to precisely control the particle size of the as-prepared magnetic iron oxide nanoparticles (MIONs), while others could be used to prepare monodisperse particles with uniform size distributions. Some of the results presented in this review showed that magnetic oxide nanorods are more potent in MHT than polyhedral-shaped MIONs. The review shows that mixtures of polyhedral- and rod-shaped MIONs resulted in 59 and 77% cell death, while monodisperse MIONRs resulted in 95% cell death. It could thus be concluded that, for magnetic iron oxide to be effective in MHT and PTT, it is important to prepare monodisperse magnetic oxide nanorods. |
| first_indexed | 2024-12-10T04:45:06Z |
| format | Article |
| id | doaj.art-276f50cf5b684d1280ac2f56193ccbc7 |
| institution | Directory Open Access Journal |
| issn | 2191-9097 |
| language | English |
| last_indexed | 2024-12-10T04:45:06Z |
| publishDate | 2021-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Nanotechnology Reviews |
| spelling | doaj.art-276f50cf5b684d1280ac2f56193ccbc72022-12-22T02:01:45ZengDe GruyterNanotechnology Reviews2191-90972021-12-0111117619010.1515/ntrev-2022-0011Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapyMona Lijo P.0Songca Sandile P.1Ajibade Peter A.2School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209, South AfricaUniversity Teaching and Learning Office, University of KwaZulu-Natal, Howard College, Durban 4041, South AfricaSchool of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X01, Scottsville, Pietermaritzburg, 3209, South AfricaThe synthesis, characterization, and applications of iron oxide nanorods have received attention in recent years. Even though there are several studies on the biological applications of iron oxide nanoparticles, recent studies have shown that rod-shaped iron oxides are effective in magnetic hyperthermia (MHT) as therapeutic technique to treat cancer. This review focused on the synthesis and encapsulation of magnetic iron oxide nanorods (MIONRs) and their use in (MHT) and photothermal therapy (PTT) for cancer cells. Among the synthetic methods that have been used to prepare MIONRs, some could be used to precisely control the particle size of the as-prepared magnetic iron oxide nanoparticles (MIONs), while others could be used to prepare monodisperse particles with uniform size distributions. Some of the results presented in this review showed that magnetic oxide nanorods are more potent in MHT than polyhedral-shaped MIONs. The review shows that mixtures of polyhedral- and rod-shaped MIONs resulted in 59 and 77% cell death, while monodisperse MIONRs resulted in 95% cell death. It could thus be concluded that, for magnetic iron oxide to be effective in MHT and PTT, it is important to prepare monodisperse magnetic oxide nanorods.https://doi.org/10.1515/ntrev-2022-0011encapsulationiron oxide nanorodsmagnetic hyperthermiaphotothermal therapy |
| spellingShingle | Mona Lijo P. Songca Sandile P. Ajibade Peter A. Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy Nanotechnology Reviews encapsulation iron oxide nanorods magnetic hyperthermia photothermal therapy |
| title | Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| title_full | Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| title_fullStr | Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| title_full_unstemmed | Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| title_short | Synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| title_sort | synthesis and encapsulation of iron oxide nanorods for application in magnetic hyperthermia and photothermal therapy |
| topic | encapsulation iron oxide nanorods magnetic hyperthermia photothermal therapy |
| url | https://doi.org/10.1515/ntrev-2022-0011 |
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