Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease
ABSTRACT Objective: To compare muscle strength (i.e. lower- and upper-body strength) and function between physically inactive childhood-onset systemic lupus erythematosus patients (C-SLE) and healthy controls (CTRL). Methods: This was a cross-sectional study and the sample consisted of 19 C-SLE (a...
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Sociedade Brasileira de Reumatologia
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| Series: | Revista Brasileira de Reumatologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600509&lng=en&tlng=en |
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| author | Ana Jéssica Pinto Fabiana Braga Benatti Hamilton Roschel Ana Lúcia de Sá Pinto Clovis Artur Silva Adriana Maluf Elias Sallum Bruno Gualano |
| author_facet | Ana Jéssica Pinto Fabiana Braga Benatti Hamilton Roschel Ana Lúcia de Sá Pinto Clovis Artur Silva Adriana Maluf Elias Sallum Bruno Gualano |
| author_sort | Ana Jéssica Pinto |
| collection | DOAJ |
| description | ABSTRACT Objective: To compare muscle strength (i.e. lower- and upper-body strength) and function between physically inactive childhood-onset systemic lupus erythematosus patients (C-SLE) and healthy controls (CTRL). Methods: This was a cross-sectional study and the sample consisted of 19 C-SLE (age between 9 and 18 years) and 15 CTRL matched by age, sex, body mass index (BMI), and physical activity levels (assessed by accelerometry). Lower- and upper-body strength was assessed by the one-repetition-maximum (1-RM) test. Isometric strength was assessed through a handgrip dynamometer. Muscle function was evaluated by the timed-stands test (TST) and the timed-up-and-go test (TUG). Results: When compared with CTRL, C-SLE showed lower leg-press and bench-press 1-RM (p = 0.026 and p = 0.008, respectively), and a tendency toward lower handgrip strength (p = 0.052). C-SLE showed lower TST scores (p = 0.036) and a tendency toward higher TUG scores (p = 0.070) when compared with CTRL. Conclusion: Physically inactive C-SLE patients with very mild disease showed reduced muscle strength and functionality when compared with healthy controls matched by physical activity levels. These findings suggest C-SLE patients may greatly suffer from a physically inactive lifestyle than healthy controls do. Moreover, some sub-clinical “residual” effect of the disease or its pharmacological treatment seems to affect C-SLE patients even with a well-controlled disease. |
| first_indexed | 2024-12-21T06:08:56Z |
| format | Article |
| id | doaj.art-276f993964d5484d98f602d5d1bd9e0f |
| institution | Directory Open Access Journal |
| issn | 1809-4570 |
| language | English |
| last_indexed | 2024-12-21T06:08:56Z |
| publisher | Sociedade Brasileira de Reumatologia |
| record_format | Article |
| series | Revista Brasileira de Reumatologia |
| spelling | doaj.art-276f993964d5484d98f602d5d1bd9e0f2022-12-21T19:13:34ZengSociedade Brasileira de ReumatologiaRevista Brasileira de Reumatologia1809-457056650951410.1016/j.rbre.2016.07.012S0482-50042016000600509Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild diseaseAna Jéssica PintoFabiana Braga BenattiHamilton RoschelAna Lúcia de Sá PintoClovis Artur SilvaAdriana Maluf Elias SallumBruno GualanoABSTRACT Objective: To compare muscle strength (i.e. lower- and upper-body strength) and function between physically inactive childhood-onset systemic lupus erythematosus patients (C-SLE) and healthy controls (CTRL). Methods: This was a cross-sectional study and the sample consisted of 19 C-SLE (age between 9 and 18 years) and 15 CTRL matched by age, sex, body mass index (BMI), and physical activity levels (assessed by accelerometry). Lower- and upper-body strength was assessed by the one-repetition-maximum (1-RM) test. Isometric strength was assessed through a handgrip dynamometer. Muscle function was evaluated by the timed-stands test (TST) and the timed-up-and-go test (TUG). Results: When compared with CTRL, C-SLE showed lower leg-press and bench-press 1-RM (p = 0.026 and p = 0.008, respectively), and a tendency toward lower handgrip strength (p = 0.052). C-SLE showed lower TST scores (p = 0.036) and a tendency toward higher TUG scores (p = 0.070) when compared with CTRL. Conclusion: Physically inactive C-SLE patients with very mild disease showed reduced muscle strength and functionality when compared with healthy controls matched by physical activity levels. These findings suggest C-SLE patients may greatly suffer from a physically inactive lifestyle than healthy controls do. Moreover, some sub-clinical “residual” effect of the disease or its pharmacological treatment seems to affect C-SLE patients even with a well-controlled disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600509&lng=en&tlng=enForça muscularCapacidade funcionalDoença reumáticaNível de atividade física |
| spellingShingle | Ana Jéssica Pinto Fabiana Braga Benatti Hamilton Roschel Ana Lúcia de Sá Pinto Clovis Artur Silva Adriana Maluf Elias Sallum Bruno Gualano Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease Revista Brasileira de Reumatologia Força muscular Capacidade funcional Doença reumática Nível de atividade física |
| title | Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease |
| title_full | Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease |
| title_fullStr | Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease |
| title_full_unstemmed | Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease |
| title_short | Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease |
| title_sort | poor muscle strength and function in physically inactive childhood onset systemic lupus erythematosus despite very mild disease |
| topic | Força muscular Capacidade funcional Doença reumática Nível de atividade física |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000600509&lng=en&tlng=en |
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