Development of a quantitative prediction algorithm for target organ-specific similarity of human pluripotent stem cell-derived organoids and cells
Quantitative methods to assess the quality of hPSC-derived organoids have not been developed. Here they present a prediction algorithm to assess the transcriptomic similarity between hPSC-derived organoids and the corresponding human target organs and perform validation on lung bud organoids, antral...
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Bibliographic Details
| Main Authors: |
Mi-Ok Lee,
Su-gi Lee,
Cho-Rok Jung,
Ye Seul Son,
Jae-Woon Ryu,
Kwang Bo Jung,
Jun-Ho Ahn,
Jung-Hwa Oh,
Hyang-Ae Lee,
Jung Hwa Lim,
Janghwan Kim,
Insu Jang,
Jinhyuk Choi,
Jaeeun Jung,
Kunhyang Park,
Byungwook Lee,
Dae-Soo Kim,
Mi-Young Son,
Hyun-Soo Cho |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-24746-w
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