The maturation of iPS cell-derived brain microvascular endothelial cells by inducible-SOX18 expression
Abstract Background Brain microvascular endothelial cells (BMECs) play a major role in the blood–brain barrier (BBB), and are critical for establishing an in vitro BBB model. Currently, iPSC-derived BMECs (iBMECs) have been used to construct in vitro BBB models with physiological barrier functions,...
Main Authors: | Hongyan Zhang, Tomoko Yamaguchi, Kenji Kawabata |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12987-023-00408-5 |
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