Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries
Background: Fine particulate matter (PM2.5) produced by landscape fires is thought to be more toxic than that from non-fire sources. However, the effects of “fire-sourced” PM2.5 on acute respiratory infection (ARI) are unknown. Methods: We combined Demographic and Health Survey (DHS) data from 48 co...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Environment International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S016041202200592X |
| _version_ | 1797948297252438016 |
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| author | Jiajianghui Li Yutong Samuel Cai Frank J. Kelly Martin J. Wooster Yiqun Han Yixuan Zheng Tianjia Guan Pengfei Li Tong Zhu Tao Xue |
| author_facet | Jiajianghui Li Yutong Samuel Cai Frank J. Kelly Martin J. Wooster Yiqun Han Yixuan Zheng Tianjia Guan Pengfei Li Tong Zhu Tao Xue |
| author_sort | Jiajianghui Li |
| collection | DOAJ |
| description | Background: Fine particulate matter (PM2.5) produced by landscape fires is thought to be more toxic than that from non-fire sources. However, the effects of “fire-sourced” PM2.5 on acute respiratory infection (ARI) are unknown. Methods: We combined Demographic and Health Survey (DHS) data from 48 countries with gridded global estimates of PM2.5 concentrations from 2003 to 2014. The proportions of fire-sourced PM2.5 were assessed by a chemical transport model using a variety of PM2.5 source data. We tested for associations between ARI and short-term exposure to fire- and “non-fire-sourced” PM2.5 using a bidirectional case-crossover analysis. The robustness and homogeneity of the associations were examined by sensitivity analyses. We also established a nonlinear exposure–response relationship between fire- and non-fire-sourced PM2.5 and ARI using a two-dimensional spline function. Results: The study included 36,432 children under 5 years who reported ARI symptoms. Each 1 µg/m3 increment of fire-sourced PM2.5 was associated with a 3.2 % (95 % confidence interval [CI] 0.2, 6.2) increment in the risk of ARI. This effect was comparable to that of each ∼5 µg/m3 increment in PM2.5 from non-fire sources (3.1 %; 95 % CI 2.4, 3.7). The association between ARI and total PM2.5 concentration was significantly mediated by the proportion of fire-sourced particles. Nonlinear analysis showed that the risk of ARI was increased by both fire- and non-fire-sourced PM2.5, but especially by the former. Conclusions: PM2.5 produced by landscape fire was more strongly associated to ARI among children under 5 years than that from non-fire sources. |
| first_indexed | 2024-04-10T21:41:08Z |
| format | Article |
| id | doaj.art-277287b2dbd64329a04d281adde6e174 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-04-10T21:41:08Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-277287b2dbd64329a04d281adde6e1742023-01-19T04:16:08ZengElsevierEnvironment International0160-41202023-01-01171107665Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countriesJiajianghui Li0Yutong Samuel Cai1Frank J. Kelly2Martin J. Wooster3Yiqun Han4Yixuan Zheng5Tianjia Guan6Pengfei Li7Tong Zhu8Tao Xue9Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing 100191, ChinaCentre for Environmental Health and Sustainability, University of Leicester, Leicester, UK; National Institute for Health Protection Research Unit in Environmental Exposures and Health, University of Leicester, Leicester, UKEnvironmental Research Group, MRC Centre for Environment and Health, Imperial College London, London, UKLeverhulme Centre for Wildfires, Environment & Society and NERC National Centre for Earth Observation, Department of Geography, King's College London, London, UKEnvironmental Research Group, MRC Centre for Environment and Health, Imperial College London, London, UKDepartment of Health Policy, School of Health Policy and Management, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaCenter of Air Quality Simulation and System Analysis, Chinese Academy of Environmental Planning, ChinaInstitute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing 100191, ChinaCollege of Environmental Sciences and Engineering, Peking University Beijing, ChinaInstitute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing 100191, China; Corresponding author.Background: Fine particulate matter (PM2.5) produced by landscape fires is thought to be more toxic than that from non-fire sources. However, the effects of “fire-sourced” PM2.5 on acute respiratory infection (ARI) are unknown. Methods: We combined Demographic and Health Survey (DHS) data from 48 countries with gridded global estimates of PM2.5 concentrations from 2003 to 2014. The proportions of fire-sourced PM2.5 were assessed by a chemical transport model using a variety of PM2.5 source data. We tested for associations between ARI and short-term exposure to fire- and “non-fire-sourced” PM2.5 using a bidirectional case-crossover analysis. The robustness and homogeneity of the associations were examined by sensitivity analyses. We also established a nonlinear exposure–response relationship between fire- and non-fire-sourced PM2.5 and ARI using a two-dimensional spline function. Results: The study included 36,432 children under 5 years who reported ARI symptoms. Each 1 µg/m3 increment of fire-sourced PM2.5 was associated with a 3.2 % (95 % confidence interval [CI] 0.2, 6.2) increment in the risk of ARI. This effect was comparable to that of each ∼5 µg/m3 increment in PM2.5 from non-fire sources (3.1 %; 95 % CI 2.4, 3.7). The association between ARI and total PM2.5 concentration was significantly mediated by the proportion of fire-sourced particles. Nonlinear analysis showed that the risk of ARI was increased by both fire- and non-fire-sourced PM2.5, but especially by the former. Conclusions: PM2.5 produced by landscape fire was more strongly associated to ARI among children under 5 years than that from non-fire sources.http://www.sciencedirect.com/science/article/pii/S016041202200592XLandscape fire, PM2.5Acute respiratory infectionChildren under 5 years of ageLow- and middle-income countriesCase-crossover study |
| spellingShingle | Jiajianghui Li Yutong Samuel Cai Frank J. Kelly Martin J. Wooster Yiqun Han Yixuan Zheng Tianjia Guan Pengfei Li Tong Zhu Tao Xue Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries Environment International Landscape fire, PM2.5 Acute respiratory infection Children under 5 years of age Low- and middle-income countries Case-crossover study |
| title | Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries |
| title_full | Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries |
| title_fullStr | Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries |
| title_full_unstemmed | Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries |
| title_short | Landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age: Findings of a case-crossover study for 48 low- and middle-income countries |
| title_sort | landscape fire smoke enhances the association between fine particulate matter exposure and acute respiratory infection among children under 5 years of age findings of a case crossover study for 48 low and middle income countries |
| topic | Landscape fire, PM2.5 Acute respiratory infection Children under 5 years of age Low- and middle-income countries Case-crossover study |
| url | http://www.sciencedirect.com/science/article/pii/S016041202200592X |
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