A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms

Posterior cortical atrophy (PCA) is a rare neurodegenerative disorder characterized by predominant visual deficits due to its atrophy of the occipital lobes. Patients typically have preserved cognitive function during the early stages, making diagnosis more difficult when compared to other neurocogn...

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Main Authors: Tremearne Hotz, Manu Sharma, Bharat Narapareddy
Format: Article
Language:English
Published: Hindawi Limited 2024-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2024/2220082
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author Tremearne Hotz
Manu Sharma
Bharat Narapareddy
author_facet Tremearne Hotz
Manu Sharma
Bharat Narapareddy
author_sort Tremearne Hotz
collection DOAJ
description Posterior cortical atrophy (PCA) is a rare neurodegenerative disorder characterized by predominant visual deficits due to its atrophy of the occipital lobes. Patients typically have preserved cognitive function during the early stages, making diagnosis more difficult when compared to other neurocognitive disorders. In this case, the patient presented predominantly with mood symptoms, delusions, and visual hallucinations. The disease course began 5 years ago with anxiety and insomnia. It developed into depressive symptoms including two suicide attempts (SAs), paranoia, and hallucinations. The diagnosis was eventually reached utilizing a thorough clinical exam, neuropsychological testing, MRI, positron emission tomography (PET), and dopamine transporter (DAT) scans. We conclude that mood or psychotic symptoms that emerge, escalate, or change dramatically at later ages merit further workup to evaluate for underlying neurodegenerative disorders.
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spelling doaj.art-2775cfb1167c46f186e9e75275fda9d22024-02-16T00:00:03ZengHindawi LimitedCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/2220082A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic SymptomsTremearne Hotz0Manu Sharma1Bharat Narapareddy2Department of PsychiatryDepartment of PsychiatryDepartment of PsychiatryPosterior cortical atrophy (PCA) is a rare neurodegenerative disorder characterized by predominant visual deficits due to its atrophy of the occipital lobes. Patients typically have preserved cognitive function during the early stages, making diagnosis more difficult when compared to other neurocognitive disorders. In this case, the patient presented predominantly with mood symptoms, delusions, and visual hallucinations. The disease course began 5 years ago with anxiety and insomnia. It developed into depressive symptoms including two suicide attempts (SAs), paranoia, and hallucinations. The diagnosis was eventually reached utilizing a thorough clinical exam, neuropsychological testing, MRI, positron emission tomography (PET), and dopamine transporter (DAT) scans. We conclude that mood or psychotic symptoms that emerge, escalate, or change dramatically at later ages merit further workup to evaluate for underlying neurodegenerative disorders.http://dx.doi.org/10.1155/2024/2220082
spellingShingle Tremearne Hotz
Manu Sharma
Bharat Narapareddy
A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
Case Reports in Psychiatry
title A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
title_full A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
title_fullStr A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
title_full_unstemmed A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
title_short A Case of Posterior Cortical Atrophy Presenting with Mood and Psychotic Symptoms
title_sort case of posterior cortical atrophy presenting with mood and psychotic symptoms
url http://dx.doi.org/10.1155/2024/2220082
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