Clustering human dental pulp fibroblasts spontaneously activate NLRP3 and AIM2 inflammasomes and induce IL-1β secretion

Clustering human dental pulp fibroblasts spontaneously activate NLRP3 and AIM2 inflammasomes and induce IL-1β secretion

Objectives: The objective of the present study was to investigate whether NOD-like receptor family pyrin domain-containing 3 (NLRP3) and absent in melanoma 2 (AIM2) inflammasomes pathways were involved in an experimental model of fibroblast activation named nemosis, which was used to mimic circumsta...

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Bibliographic Details
Main Authors: Shafei Zhai, Lihui Zhang, Xue Li, Qi Yu, Changkui Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Regenerative Therapy
Subjects:
Dental pulp fibroblast
Nemosis
Inflammasome
Pyrin domain-containing 3
Absent in melanoma 2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424000245

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