Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent
Inflammation of the post-partum uterus is a normal physiological event, crucial for tissue involution and repair. However, in the bovine, some cows fail to resolve this inflammation, resulting in endometritis, which compromises fertility. Earlier work has identified upregulated expression of the pot...
Main Authors: | Paul Kelly, Kieran G. Meade, Cliona O'Farrelly |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.00102/full |
Similar Items
-
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3
by: Liangli Song, et al.
Published: (2023-12-01) -
The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
by: Yang Gyun Kim, et al.
Published: (2019-11-01) -
Role of Porphyromonas gingivalis in the downregulation of NLRp3 inflammasome in periodontitis
by: Neelam Gavali, et al.
Published: (2022-01-01) -
Fantastic voyage: The journey of NLRP3 inflammasome activation
by: Xiangyong Que, et al.
Published: (2024-03-01) -
Neuroprotective effects of human umbilical cord mesenchymal stromal cells in PD mice via centrally and peripherally suppressing NLRP3 inflammasome-mediated inflammatory responses
by: Liping Zhou, et al.
Published: (2022-09-01)