Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry

Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry

A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-source decay (MALDI-ISD) to investigate heter...

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Bibliographic Details
Main Authors: Bao Quoc Tran, Christopher Barton, Jinhua Feng, Aimee Sandjong, Sung Hwan Yoon, Shivangi Awasthi, Tao Liang, Mohd M. Khan, David P.A. Kilgour, David R. Goodlett, Young Ah Goo
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340915003261

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