Cannabinoid WIN55,212-2 reprograms monocytes and macrophages to inhibit LPS-induced inflammation

Cannabinoid WIN55,212-2 reprograms monocytes and macrophages to inhibit LPS-induced inflammation

IntroductionChronic or uncontrolled activation of myeloid cells including monocytes, macrophages and dendritic cells (DCs) is a hallmark of immune-mediated inflammatory disorders. There is an urgent need for the development of novel drugs with the capacity to impair innate immune cell overactivation...

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Bibliographic Details
Main Authors: Mario Pérez-Diego, Alba Angelina, Leticia Martín-Cruz, Andrés de la Rocha-Muñoz, Angel Maldonado, Carmen Sevilla-Ortega, Oscar Palomares
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
cannabinoids
WIN55,212-2
monocyte differentiation
macrophage polarization
immunomodulation
anti-inflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1147520/full

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