Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice

Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice

Repeated mild traumatic brain injury (rmTBI) can lead to development of chronic traumatic encephalopathy (CTE), which is characterized by progressive neurodegeneration with presence of white matter damage, gliosis and hyper-phosphorylated tau. While animal models of rmTBI have been documented, few c...

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Bibliographic Details
Main Authors: Hank Cheng, Lisa M. Deaton, Minhua Qiu, Sukwon Ha, Reynand Pacoma, Jianmin Lao, Valerie Tolley, Rita Moran, Amber Keeton, John R. Lamb, John Fathman, John R. Walker, Andrew M. Schumacher
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Traumatic brain injury
Chronic traumatic encephalopathy
White matter
Tau
Neuroinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303584

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