Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure
Background/Aim. Interatrial conduction time is early marker of disturbed impulse propagation in adult with elevated blood pressure. The aim of our study was to evaluate significance of noninvasive echocardiographic marker of slow sinus impulse propagation (atrial conduction time) for the identificat...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2020-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84501800101D.pdf |
| _version_ | 1819063679691259904 |
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| author | Đikić Dijana Mujović Nebojša Giga Vojislav Marinković Milan Trajković Goran Lazić Snežana Pavlović Vedrana Perić Vladan Simić Dragan |
| author_facet | Đikić Dijana Mujović Nebojša Giga Vojislav Marinković Milan Trajković Goran Lazić Snežana Pavlović Vedrana Perić Vladan Simić Dragan |
| author_sort | Đikić Dijana |
| collection | DOAJ |
| description | Background/Aim. Interatrial conduction time is early marker of disturbed impulse propagation in adult with elevated blood pressure. The aim of our study was to evaluate significance of noninvasive echocardiographic marker of slow sinus impulse propagation (atrial conduction time) for the identification of persons with slightly elevated blood pressure and hypertension in adults. Methods. One hundred and forty nine adults with normal and elevated blood pressure were studied: 46 normotensive adults (group 1), 28 adults with elevated blood pressure and hypertension stage 1 (group 2) and 75 adults with hypertension stage 2 (group 3), based on the Joint National Committee 8 (JNC-8) hypertension guidelines. We studied P wave dispersion, reservoir function of the left atrium (LA), total emptying volume of the LA and total emptying fraction of the LA (LATEF). The atrial conduction time (ACT) was evaluated by the pulsed tissue Doppler, and expressed as interatrial and intraatrial conduction time. Results. The LATEF decreased progressively from the group 3 (64.8 ± 4.4%) to the group 2 (59.8 ± 5.2%) and the group 1 (55.6 ± 7.3%) (p < 0.001). The P wave dispersion (55.1 ± 9.8 ms vs. 46.8 ± 3.1 ms vs. 43.1 ± 2.6 ms; p < 0.01) and intra ACT were significantly prolonged only in the group 3 compared to the other groups (22.7 ± 11.0 ms vs. 8.4 ± 4.7ms vs. 5.6 ± 2.4 ms, respectively; p < 0.001). Inter ACT significantly increased from the group 1 to the group 2 and the group 3 (15.6 ± 3.9 ms vs. 24.6 ± 5.7 ms vs. 50.4 ± 20 ms, respectively; p < 0.05). Using a cut-off level of 19.5 ms, inter ACT could separate adults in the group 2 from the group 1 with a sensitivity of 85%, and specificity of 89% [area under receiver operating characteristic (ROC) curve 0.911]. Conclusion. Prolonged ACT estimated with the tissue Doppler may be useful for identification persons with slighty elevated blood pressure, and hypertension stage 1. |
| first_indexed | 2024-12-21T15:18:31Z |
| format | Article |
| id | doaj.art-277e55334ae744a3b9e8e72603e5f9e6 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-12-21T15:18:31Z |
| publishDate | 2020-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-277e55334ae744a3b9e8e72603e5f9e62022-12-21T18:59:06ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202020-01-0177656957410.2298/VSP180417101D0042-84501800101DInteratrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressureĐikić Dijana0Mujović Nebojša1Giga Vojislav2Marinković Milan3Trajković Goran4Lazić Snežana5Pavlović Vedrana6Perić Vladan7Simić Dragan8Clinical Centre of Serbia, Clinic of Cardiology, Belgrade, SerbiaClinical Centre of Serbia, Clinic of Cardiology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaClinical Centre of Serbia, Clinic of Cardiology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaClinical Centre of Serbia, Clinic of Cardiology, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Institute for Medical Statistics and Informatics, Belgrade, SerbiaUniversity of Priština, Faculty of Medicine, Kosovska Mitrovica, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Institute for Medical Statistics and Informatics, Belgrade, SerbiaUniversity of Priština, Faculty of Medicine, Kosovska Mitrovica, SerbiaClinical Centre of Serbia, Clinic of Cardiology, Belgrade, Serbia + University of Belgrade, Faculty of Medicine, Belgrade, SerbiaBackground/Aim. Interatrial conduction time is early marker of disturbed impulse propagation in adult with elevated blood pressure. The aim of our study was to evaluate significance of noninvasive echocardiographic marker of slow sinus impulse propagation (atrial conduction time) for the identification of persons with slightly elevated blood pressure and hypertension in adults. Methods. One hundred and forty nine adults with normal and elevated blood pressure were studied: 46 normotensive adults (group 1), 28 adults with elevated blood pressure and hypertension stage 1 (group 2) and 75 adults with hypertension stage 2 (group 3), based on the Joint National Committee 8 (JNC-8) hypertension guidelines. We studied P wave dispersion, reservoir function of the left atrium (LA), total emptying volume of the LA and total emptying fraction of the LA (LATEF). The atrial conduction time (ACT) was evaluated by the pulsed tissue Doppler, and expressed as interatrial and intraatrial conduction time. Results. The LATEF decreased progressively from the group 3 (64.8 ± 4.4%) to the group 2 (59.8 ± 5.2%) and the group 1 (55.6 ± 7.3%) (p < 0.001). The P wave dispersion (55.1 ± 9.8 ms vs. 46.8 ± 3.1 ms vs. 43.1 ± 2.6 ms; p < 0.01) and intra ACT were significantly prolonged only in the group 3 compared to the other groups (22.7 ± 11.0 ms vs. 8.4 ± 4.7ms vs. 5.6 ± 2.4 ms, respectively; p < 0.001). Inter ACT significantly increased from the group 1 to the group 2 and the group 3 (15.6 ± 3.9 ms vs. 24.6 ± 5.7 ms vs. 50.4 ± 20 ms, respectively; p < 0.05). Using a cut-off level of 19.5 ms, inter ACT could separate adults in the group 2 from the group 1 with a sensitivity of 85%, and specificity of 89% [area under receiver operating characteristic (ROC) curve 0.911]. Conclusion. Prolonged ACT estimated with the tissue Doppler may be useful for identification persons with slighty elevated blood pressure, and hypertension stage 1.http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84501800101D.pdfblood presurehypertensionechocardiography, dopplerelectrocardiographydiagnosis |
| spellingShingle | Đikić Dijana Mujović Nebojša Giga Vojislav Marinković Milan Trajković Goran Lazić Snežana Pavlović Vedrana Perić Vladan Simić Dragan Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure Vojnosanitetski Pregled blood presure hypertension echocardiography, doppler electrocardiography diagnosis |
| title | Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| title_full | Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| title_fullStr | Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| title_full_unstemmed | Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| title_short | Interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| title_sort | interatrial conduction time is early marker of disturbed impulse propagation in adults with slightly elevated blood pressure |
| topic | blood presure hypertension echocardiography, doppler electrocardiography diagnosis |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2020/0042-84501800101D.pdf |
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