The Use of Tranexamic Acid in Dermatology

Tranexamic acid is a synthetic derivative of the amino acid lysine, an antifibrinolytic that is primarily used to reduce bleeding in surgery, trauma, and dental procedures. Its anti-inflammatory and anti-angiogenic properties, as well as its ability to suppress melanogenesis have enabled it to be...

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Main Authors: Klara Gaćina, Anđela Krstanović Ćosić
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2023-01-01
Series:Acta Clinica Croatica
Subjects:
Online Access:https://hrcak.srce.hr/file/445795
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author Klara Gaćina
Anđela Krstanović Ćosić
author_facet Klara Gaćina
Anđela Krstanović Ćosić
author_sort Klara Gaćina
collection DOAJ
description Tranexamic acid is a synthetic derivative of the amino acid lysine, an antifibrinolytic that is primarily used to reduce bleeding in surgery, trauma, and dental procedures. Its anti-inflammatory and anti-angiogenic properties, as well as its ability to suppress melanogenesis have enabled it to be used in dermatology in the treatment of skin conditions such as melasma, acne, post-inflammatory hyperpigmentation, rosacea and angioedema. Tranexamic acid can be used by various routes of administration including oral, topical and intradermal injection, and in combination with other treatment methods. This review article presents evidence for the effectiveness of tranexamic acid in the treatment of various skin disorders.
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spelling doaj.art-2781942f99bb4c64ae4194156d3559302024-04-15T18:57:40ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512023-01-0162.236837110.20471/acc.2023.62.02.16The Use of Tranexamic Acid in DermatologyKlara Gaćina0Anđela Krstanović Ćosić1Mladen Prlina Primary Care Medical Practice, Zagreb, CroatiaAlen Ahmetović Dental Practice, Gornja Stubica, CroatiaTranexamic acid is a synthetic derivative of the amino acid lysine, an antifibrinolytic that is primarily used to reduce bleeding in surgery, trauma, and dental procedures. Its anti-inflammatory and anti-angiogenic properties, as well as its ability to suppress melanogenesis have enabled it to be used in dermatology in the treatment of skin conditions such as melasma, acne, post-inflammatory hyperpigmentation, rosacea and angioedema. Tranexamic acid can be used by various routes of administration including oral, topical and intradermal injection, and in combination with other treatment methods. This review article presents evidence for the effectiveness of tranexamic acid in the treatment of various skin disorders.https://hrcak.srce.hr/file/445795Tranexamic acidDermatologyMelasmaAcneRosaceaAngioedema
spellingShingle Klara Gaćina
Anđela Krstanović Ćosić
The Use of Tranexamic Acid in Dermatology
Acta Clinica Croatica
Tranexamic acid
Dermatology
Melasma
Acne
Rosacea
Angioedema
title The Use of Tranexamic Acid in Dermatology
title_full The Use of Tranexamic Acid in Dermatology
title_fullStr The Use of Tranexamic Acid in Dermatology
title_full_unstemmed The Use of Tranexamic Acid in Dermatology
title_short The Use of Tranexamic Acid in Dermatology
title_sort use of tranexamic acid in dermatology
topic Tranexamic acid
Dermatology
Melasma
Acne
Rosacea
Angioedema
url https://hrcak.srce.hr/file/445795
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