Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy
This case report describes the re-administration of abatacept to successfully reduce the articularsymptoms of a patient with rheumatoid arthritisduring the intensive phase of anti-tuberculous therapy. A 75-year-old man developed active pulmonary tuberculosis during the administration of abatacept fo...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-01-01
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| Series: | Respiratory Medicine Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007117300631 |
| _version_ | 1819273981840064512 |
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| author | Hironori Kawamoto, M.D. Jin Takasaki Satoru Ishii Manabu Suzuki Eriko Morino Go Naka Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Haruhito Sugiyama |
| author_facet | Hironori Kawamoto, M.D. Jin Takasaki Satoru Ishii Manabu Suzuki Eriko Morino Go Naka Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Haruhito Sugiyama |
| author_sort | Hironori Kawamoto, M.D. |
| collection | DOAJ |
| description | This case report describes the re-administration of abatacept to successfully reduce the articularsymptoms of a patient with rheumatoid arthritisduring the intensive phase of anti-tuberculous therapy. A 75-year-old man developed active pulmonary tuberculosis during the administration of abatacept for rheumatoid arthritis. The patient experienced a paradoxical reaction and exacerbation of rheumatoid arthritis that caused us to discontinue the abatacept. Later re-administration of abatacept along with anti-tuberculosis treatment led to well-controlled rheumatoid arthritis without exacerbation of the tuberculosis. This case shows that re-administration of abatacept may be much safer than TNF inhibitor to treat patients who are infected with mycobacteria during thetreatment of immunological diseases such asrheumatoid arthritiswith biological agents. |
| first_indexed | 2024-12-23T23:01:10Z |
| format | Article |
| id | doaj.art-2782924252f84758b38339fe7eb8f052 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-23T23:01:10Z |
| publishDate | 2017-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-2782924252f84758b38339fe7eb8f0522022-12-21T17:26:54ZengElsevierRespiratory Medicine Case Reports2213-00712017-01-0121C14715010.1016/j.rmcr.2017.04.013Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapyHironori Kawamoto, M.D.0Jin Takasaki1Satoru Ishii2Manabu Suzuki3Eriko Morino4Go Naka5Motoyasu Iikura6Shinyu Izumi7Yuichiro Takeda8Haruhito Sugiyama9Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, Kohnodai Hospital, National Center for Global Health and Medicine, Tokyo, JapanDivision of Respiratory Diseases, Department of Internal Medicine, National Center for Global Health and Medicine, Tokyo, JapanThis case report describes the re-administration of abatacept to successfully reduce the articularsymptoms of a patient with rheumatoid arthritisduring the intensive phase of anti-tuberculous therapy. A 75-year-old man developed active pulmonary tuberculosis during the administration of abatacept for rheumatoid arthritis. The patient experienced a paradoxical reaction and exacerbation of rheumatoid arthritis that caused us to discontinue the abatacept. Later re-administration of abatacept along with anti-tuberculosis treatment led to well-controlled rheumatoid arthritis without exacerbation of the tuberculosis. This case shows that re-administration of abatacept may be much safer than TNF inhibitor to treat patients who are infected with mycobacteria during thetreatment of immunological diseases such asrheumatoid arthritiswith biological agents.http://www.sciencedirect.com/science/article/pii/S2213007117300631TuberculosisBiological agentAbataceptParadoxical reactionRheumatoid arthritis |
| spellingShingle | Hironori Kawamoto, M.D. Jin Takasaki Satoru Ishii Manabu Suzuki Eriko Morino Go Naka Motoyasu Iikura Shinyu Izumi Yuichiro Takeda Haruhito Sugiyama Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy Respiratory Medicine Case Reports Tuberculosis Biological agent Abatacept Paradoxical reaction Rheumatoid arthritis |
| title | Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy |
| title_full | Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy |
| title_fullStr | Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy |
| title_full_unstemmed | Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy |
| title_short | Re-administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti-tuberculous therapy |
| title_sort | re administration of abatacept for the control of articular symptoms of rheumatoid arthritis during anti tuberculous therapy |
| topic | Tuberculosis Biological agent Abatacept Paradoxical reaction Rheumatoid arthritis |
| url | http://www.sciencedirect.com/science/article/pii/S2213007117300631 |
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