Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia

Age-related cataract is a major medical and social issue as it is the main cause of reversible blindness in the world. Age-related cataract is frequently accompanied by pseudoexfoliation syndrome (PXFS) - a systemic dystrophic process, clinically manifested in the eyeball. Dystrophic changes in XFS...

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Main Authors: A. A. Polapina, E. N. Komarovskikh, S. N. Sakhnov, A. G. Zabolotny
Format: Article
Language:Russian
Published: Real Time Ltd 2018-10-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/165
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author A. A. Polapina
E. N. Komarovskikh
S. N. Sakhnov
A. G. Zabolotny
author_facet A. A. Polapina
E. N. Komarovskikh
S. N. Sakhnov
A. G. Zabolotny
author_sort A. A. Polapina
collection DOAJ
description Age-related cataract is a major medical and social issue as it is the main cause of reversible blindness in the world. Age-related cataract is frequently accompanied by pseudoexfoliation syndrome (PXFS) - a systemic dystrophic process, clinically manifested in the eyeball. Dystrophic changes in XFS bring about a 5-fold increase of the risk of cataract surgery complications, amounting to 49.4 % of cases. Purpose: to study the clinical characteristics of ocular PXFS manifestations in age-related cataract among residents of the South of Russia. Material and methods. A total of 179 patients (277 eyes) with age-related cataract were tested. Of these, 75 patients (41.9 %, 114 eyes) were found to have PXFS while the remaining 104 patients (58.1 %, 163 eyes) had no PXFS. Testing included visometry, autokeratorefractometry, ophthalmic biomicroscopy, pneumotonometry, perimetry, ophthalmoscopy, ultrasound biometry, determination of electrical sensitivity threshold of the optic nerve, and critical flicker frequency. Results. It was found that age-related cataract patients with PXFS were significantly older than those without PXFS. The former showed a lower initial visual acuity and pronounced trophic changes in the anterior segment of the eye. PXFS patients developed iridodonesis 13 times as often as those without PXFS, while lens subluxation occurred 8 times as often. In more than one third of the cases, PXFS patients had dense or very dense lens nucleus. Conclusion. Age-related cataract of South Russia residents having pseudoexfoliation syndrome was found to be more severe and complication-prone than that of patients without PXFS. For citation: Polapina A.A., Komarovskikh E.N., Sakhnov S.N., Zabolotny A.G. Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia. Russian ophthalmological journal. 2018; 11(3): 19-24 (In Russian). doi: 10.21516/2072-0076-2018-11-3-19-24.
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spelling doaj.art-27859da14aab41088028170f9f7fb7152025-03-02T09:51:25ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-01113192410.21516/2072-0076-2018-11-3-19-24165Age-related cataract and pseudoexfoliation syndrome among residents of the south of RussiaA. A. Polapina0E. N. Komarovskikh1S. N. Sakhnov2A. G. Zabolotny3Kuban State Medical University, Krasnodar, RussiaKuban State Medical University, Krasnodar, RussiaKuban State Medical University, Krasnodar, RussiaKuban State Medical University, Krasnodar, RussiaAge-related cataract is a major medical and social issue as it is the main cause of reversible blindness in the world. Age-related cataract is frequently accompanied by pseudoexfoliation syndrome (PXFS) - a systemic dystrophic process, clinically manifested in the eyeball. Dystrophic changes in XFS bring about a 5-fold increase of the risk of cataract surgery complications, amounting to 49.4 % of cases. Purpose: to study the clinical characteristics of ocular PXFS manifestations in age-related cataract among residents of the South of Russia. Material and methods. A total of 179 patients (277 eyes) with age-related cataract were tested. Of these, 75 patients (41.9 %, 114 eyes) were found to have PXFS while the remaining 104 patients (58.1 %, 163 eyes) had no PXFS. Testing included visometry, autokeratorefractometry, ophthalmic biomicroscopy, pneumotonometry, perimetry, ophthalmoscopy, ultrasound biometry, determination of electrical sensitivity threshold of the optic nerve, and critical flicker frequency. Results. It was found that age-related cataract patients with PXFS were significantly older than those without PXFS. The former showed a lower initial visual acuity and pronounced trophic changes in the anterior segment of the eye. PXFS patients developed iridodonesis 13 times as often as those without PXFS, while lens subluxation occurred 8 times as often. In more than one third of the cases, PXFS patients had dense or very dense lens nucleus. Conclusion. Age-related cataract of South Russia residents having pseudoexfoliation syndrome was found to be more severe and complication-prone than that of patients without PXFS. For citation: Polapina A.A., Komarovskikh E.N., Sakhnov S.N., Zabolotny A.G. Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia. Russian ophthalmological journal. 2018; 11(3): 19-24 (In Russian). doi: 10.21516/2072-0076-2018-11-3-19-24.https://roj.igb.ru/jour/article/view/165возрастная катарактапсевдоэксфолиативный синдромюжные регионы россииage-related cataractspseudoexfoliation syndrome (xfs)southern russia
spellingShingle A. A. Polapina
E. N. Komarovskikh
S. N. Sakhnov
A. G. Zabolotny
Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
Российский офтальмологический журнал
возрастная катаракта
псевдоэксфолиативный синдром
южные регионы россии
age-related cataracts
pseudoexfoliation syndrome (xfs)
southern russia
title Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
title_full Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
title_fullStr Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
title_full_unstemmed Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
title_short Age-related cataract and pseudoexfoliation syndrome among residents of the south of Russia
title_sort age related cataract and pseudoexfoliation syndrome among residents of the south of russia
topic возрастная катаракта
псевдоэксфолиативный синдром
южные регионы россии
age-related cataracts
pseudoexfoliation syndrome (xfs)
southern russia
url https://roj.igb.ru/jour/article/view/165
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AT snsakhnov agerelatedcataractandpseudoexfoliationsyndromeamongresidentsofthesouthofrussia
AT agzabolotny agerelatedcataractandpseudoexfoliationsyndromeamongresidentsofthesouthofrussia