Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency

We are presenting a rare case of bilateral adrenal non-Hodgkin′s lymphoma (NHL) that presented as a primary malignancy. An 83-year-old man presented with newly discovered bilateral adrenal incidentalomas, fatigue, and 30 pound weight loss. Of the 116 cases of primary adrenal NHL reported, over half...

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Main Authors: William Greg Simpson, Paurush Babbar, Lynnetta Faith Payne
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Urology Annals
Subjects:
Online Access:http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=2;spage=259;epage=261;aulast=Simpson
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author William Greg Simpson
Paurush Babbar
Lynnetta Faith Payne
author_facet William Greg Simpson
Paurush Babbar
Lynnetta Faith Payne
author_sort William Greg Simpson
collection DOAJ
description We are presenting a rare case of bilateral adrenal non-Hodgkin′s lymphoma (NHL) that presented as a primary malignancy. An 83-year-old man presented with newly discovered bilateral adrenal incidentalomas, fatigue, and 30 pound weight loss. Of the 116 cases of primary adrenal NHL reported, over half have presented bilaterally and occur with adrenal insufficiency. Therefore, the finding of bilateral adrenal masses requires an urgent work-up of the functional status of the adrenal gland as well as a thorough analysis of the imaging characteristics seen on noncontrast computed tomography (CT) in order to maximize patient survival. Adrenal function testing was normal. Repeat CT imaging revealed rapidly growing lesions with high attenuations; both masses >10 HU. Histological examination of core biopsies discovered malignant lymphoma with no known past history of lymphoma. Our case coincides with the literature, which states that a mass with attenuation >10 HU in the adrenal glands has a high risk of malignancy.
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spelling doaj.art-278892fd25ac46bfb2a7d4b28b980a492022-12-22T03:30:00ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342015-01-017225926110.4103/0974-7796.152942Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiencyWilliam Greg SimpsonPaurush BabbarLynnetta Faith PayneWe are presenting a rare case of bilateral adrenal non-Hodgkin′s lymphoma (NHL) that presented as a primary malignancy. An 83-year-old man presented with newly discovered bilateral adrenal incidentalomas, fatigue, and 30 pound weight loss. Of the 116 cases of primary adrenal NHL reported, over half have presented bilaterally and occur with adrenal insufficiency. Therefore, the finding of bilateral adrenal masses requires an urgent work-up of the functional status of the adrenal gland as well as a thorough analysis of the imaging characteristics seen on noncontrast computed tomography (CT) in order to maximize patient survival. Adrenal function testing was normal. Repeat CT imaging revealed rapidly growing lesions with high attenuations; both masses >10 HU. Histological examination of core biopsies discovered malignant lymphoma with no known past history of lymphoma. Our case coincides with the literature, which states that a mass with attenuation >10 HU in the adrenal glands has a high risk of malignancy.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=2;spage=259;epage=261;aulast=SimpsonExtranodalincidentalomaprimary non-Hodgkin′s lymphoma
spellingShingle William Greg Simpson
Paurush Babbar
Lynnetta Faith Payne
Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
Urology Annals
Extranodal
incidentaloma
primary non-Hodgkin′s lymphoma
title Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
title_full Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
title_fullStr Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
title_full_unstemmed Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
title_short Bilateral primary adrenal non-Hodgkin′s lymphoma without adrenal insufficiency
title_sort bilateral primary adrenal non hodgkin s lymphoma without adrenal insufficiency
topic Extranodal
incidentaloma
primary non-Hodgkin′s lymphoma
url http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=2;spage=259;epage=261;aulast=Simpson
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AT paurushbabbar bilateralprimaryadrenalnonhodgkinslymphomawithoutadrenalinsufficiency
AT lynnettafaithpayne bilateralprimaryadrenalnonhodgkinslymphomawithoutadrenalinsufficiency