Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents
AIM: To analyze the association between refractive status and refractive factors, and to explore the effectiveness of mean ocular axial length(AL), mean corneal radius of curvature(CR)and their ratio in the assessment of amitropia in children and adolescents.<p>METHODS: Cross sectional study,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2019-10-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2019/10/201910007.pdf |
| _version_ | 1819092638860574720 |
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| author | Ke-Ran Li Qiao-Lin Li Xiang-Zhong Xu Qin Jiang Jiang-Huai Cai |
| author_facet | Ke-Ran Li Qiao-Lin Li Xiang-Zhong Xu Qin Jiang Jiang-Huai Cai |
| author_sort | Ke-Ran Li |
| collection | DOAJ |
| description | AIM: To analyze the association between refractive status and refractive factors, and to explore the effectiveness of mean ocular axial length(AL), mean corneal radius of curvature(CR)and their ratio in the assessment of amitropia in children and adolescents.<p>METHODS: Cross sectional study, 816 cases(1632 eyes)aged 3-16 years old suspected ametropia were selected in the Affiliated Eye Hospital of Nanjing Medical University from December 2017 to December 2018. Uncorrected visual acuity(UCVA), mean AL and mean CR were tested. Autorefraction was performed after cycloplegia, which was measured as the spherical equivalent(SE).<p>RESULTS: Among 816 cases of children and adolescents aged 3-16, 773 were ametropia, accounting for 94.7%, with the highest proportion aged 7-14. The difference(one eye)in the mean AL, and AL/CR ratio of different refractive groups were statistically significant(<i>P</i><0.05). In different refractive states, the mean AL and AL/CR ratio showed a low correlation with SE in emmetropes and low hyperopes but higher correlation in moderately hyperopic and myopic children. The mean AL, AL/CR ratio were higher correlation with SE increased with age. Sensitivity was 0.880, specificity was 0.916, and accuracy was 89.2%. The area under ROC curve was 0.954.<p>CONCLUSION: The proportion of myopia among children and adolescents gradually increases and shows a large increase after 7 years old. The AL and AL/CR ratio showed higher correlation in moderate hyperopes, myopes and older ages. The AL/CR ratio is highly accurate in the diagnosis of myopia in adolescents and children. |
| first_indexed | 2024-12-21T22:58:48Z |
| format | Article |
| id | doaj.art-2788a111832b4ba1aa67a447ef242b90 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-21T22:58:48Z |
| publishDate | 2019-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-2788a111832b4ba1aa67a447ef242b902022-12-21T18:47:22ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232019-10-0119101667167110.3980/j.issn.1672-5123.2019.10.07Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescentsKe-Ran Li0Qiao-Lin Li1Xiang-Zhong Xu2Qin Jiang3Jiang-Huai Cai4Department of Cataract, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, ChinaDepartment of Cataract, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, ChinaDepartment of Cataract, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, ChinaDepartment of Cataract, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, ChinaDepartment of Cataract, the Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, ChinaAIM: To analyze the association between refractive status and refractive factors, and to explore the effectiveness of mean ocular axial length(AL), mean corneal radius of curvature(CR)and their ratio in the assessment of amitropia in children and adolescents.<p>METHODS: Cross sectional study, 816 cases(1632 eyes)aged 3-16 years old suspected ametropia were selected in the Affiliated Eye Hospital of Nanjing Medical University from December 2017 to December 2018. Uncorrected visual acuity(UCVA), mean AL and mean CR were tested. Autorefraction was performed after cycloplegia, which was measured as the spherical equivalent(SE).<p>RESULTS: Among 816 cases of children and adolescents aged 3-16, 773 were ametropia, accounting for 94.7%, with the highest proportion aged 7-14. The difference(one eye)in the mean AL, and AL/CR ratio of different refractive groups were statistically significant(<i>P</i><0.05). In different refractive states, the mean AL and AL/CR ratio showed a low correlation with SE in emmetropes and low hyperopes but higher correlation in moderately hyperopic and myopic children. The mean AL, AL/CR ratio were higher correlation with SE increased with age. Sensitivity was 0.880, specificity was 0.916, and accuracy was 89.2%. The area under ROC curve was 0.954.<p>CONCLUSION: The proportion of myopia among children and adolescents gradually increases and shows a large increase after 7 years old. The AL and AL/CR ratio showed higher correlation in moderate hyperopes, myopes and older ages. The AL/CR ratio is highly accurate in the diagnosis of myopia in adolescents and children.http://ies.ijo.cn/cn_publish/2019/10/201910007.pdfaxialmean corneal redius of curvatureAL/CR ratioradius ametropiamyopia |
| spellingShingle | Ke-Ran Li Qiao-Lin Li Xiang-Zhong Xu Qin Jiang Jiang-Huai Cai Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents Guoji Yanke Zazhi axial mean corneal redius of curvature AL/CR ratio radius ametropia myopia |
| title | Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| title_full | Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| title_fullStr | Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| title_full_unstemmed | Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| title_short | Effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| title_sort | effect of axial length and corneal curvature radius and their ratio on refractive errors in children and adolescents |
| topic | axial mean corneal redius of curvature AL/CR ratio radius ametropia myopia |
| url | http://ies.ijo.cn/cn_publish/2019/10/201910007.pdf |
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