The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures

The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures

Abstract The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main ep...

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Bibliographic Details
Main Authors: Giulia Sgueglia, Salvatore Longobardi, Domenico Valerio, Maria Rosaria Campitiello, Nicola Colacurci, Cinzia Di Pietro, Rosalia Battaglia, Thomas D’Hooghe, Lucia Altucci, Carmela Dell’Aversana
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
Fertility
IVF
Reproduction
Online Access:https://doi.org/10.1186/s13148-023-01490-0
Description
Summary:Abstract The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main epigenetic modifications that may influence female reproduction and could affect IVF success. Graphical Abstract
ISSN:1868-7083

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