The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures
Abstract The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main ep...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-05-01
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| Series: | Clinical Epigenetics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13148-023-01490-0 |
| _version_ | 1797832007809499136 |
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| author | Giulia Sgueglia Salvatore Longobardi Domenico Valerio Maria Rosaria Campitiello Nicola Colacurci Cinzia Di Pietro Rosalia Battaglia Thomas D’Hooghe Lucia Altucci Carmela Dell’Aversana |
| author_facet | Giulia Sgueglia Salvatore Longobardi Domenico Valerio Maria Rosaria Campitiello Nicola Colacurci Cinzia Di Pietro Rosalia Battaglia Thomas D’Hooghe Lucia Altucci Carmela Dell’Aversana |
| author_sort | Giulia Sgueglia |
| collection | DOAJ |
| description | Abstract The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main epigenetic modifications that may influence female reproduction and could affect IVF success. Graphical Abstract |
| first_indexed | 2024-04-09T14:00:50Z |
| format | Article |
| id | doaj.art-27895c5d97f64743a3b3fbae45d77154 |
| institution | Directory Open Access Journal |
| issn | 1868-7083 |
| language | English |
| last_indexed | 2024-04-09T14:00:50Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Clinical Epigenetics |
| spelling | doaj.art-27895c5d97f64743a3b3fbae45d771542023-05-07T11:16:26ZengBMCClinical Epigenetics1868-70832023-05-0115111010.1186/s13148-023-01490-0The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF proceduresGiulia Sgueglia0Salvatore Longobardi1Domenico Valerio2Maria Rosaria Campitiello3Nicola Colacurci4Cinzia Di Pietro5Rosalia Battaglia6Thomas D’Hooghe7Lucia Altucci8Carmela Dell’Aversana9Department of Precision Medicine, University of Campania ‘Luigi Vanvitelli’, Programma di Epigenetica Medica, Azienda Ospedaliera UniversitariaMerck KGaAOutpatient Fertility Unit, University of Campania ‘Luigi Vanvitelli’Department of Obstetrics and Gynecology and Physiopathology of Human Reproduction, ASL SalernoOutpatient Fertility Unit, University of Campania ‘Luigi Vanvitelli’Department of Biomedical and Biotechnological Sciences, Section of Biology and Genetics “Giovanni Sichel”, University of CataniaDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics “Giovanni Sichel”, University of CataniaMerck KGaADepartment of Precision Medicine, University of Campania ‘Luigi Vanvitelli’, Programma di Epigenetica Medica, Azienda Ospedaliera UniversitariaDepartment of Precision Medicine, University of Campania ‘Luigi Vanvitelli’, Programma di Epigenetica Medica, Azienda Ospedaliera UniversitariaAbstract The constant decline in fertility and older reproductive age is the major cause of low clinical pregnancy rates in industrialised countries. Epigenetic mechanisms impact on proper embryonic development in women undergoing in vitro fertilisation (IVF) protocols. Here, we describe the main epigenetic modifications that may influence female reproduction and could affect IVF success. Graphical Abstracthttps://doi.org/10.1186/s13148-023-01490-0EpigeneticsFertilityIVFReproduction |
| spellingShingle | Giulia Sgueglia Salvatore Longobardi Domenico Valerio Maria Rosaria Campitiello Nicola Colacurci Cinzia Di Pietro Rosalia Battaglia Thomas D’Hooghe Lucia Altucci Carmela Dell’Aversana The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures Clinical Epigenetics Epigenetics Fertility IVF Reproduction |
| title | The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures |
| title_full | The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures |
| title_fullStr | The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures |
| title_full_unstemmed | The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures |
| title_short | The impact of epigenetic landscape on ovarian cells in infertile older women undergoing IVF procedures |
| title_sort | impact of epigenetic landscape on ovarian cells in infertile older women undergoing ivf procedures |
| topic | Epigenetics Fertility IVF Reproduction |
| url | https://doi.org/10.1186/s13148-023-01490-0 |
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