ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis
The sensitivity of ALEX2 Allergy Explorer test in patients suffering from atopic dermatitis and clinical reactions to fish/shrimps was evaluated. We compared the results of specific IgE to allergen reagents (molecular components) and clinical reactions in the open exposure test (patient’s history);...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Food and Agricultural Immunology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09540105.2021.2005546 |
| _version_ | 1798034230531325952 |
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| author | J. Čelakovská E. Čermákova R. Vaňková C. Andrýs J. Krejsek |
| author_facet | J. Čelakovská E. Čermákova R. Vaňková C. Andrýs J. Krejsek |
| author_sort | J. Čelakovská |
| collection | DOAJ |
| description | The sensitivity of ALEX2 Allergy Explorer test in patients suffering from atopic dermatitis and clinical reactions to fish/shrimps was evaluated. We compared the results of specific IgE to allergen reagents (molecular components) and clinical reactions in the open exposure test (patient’s history); the sensitivity was calculated with Fisher's Exact test (Rates and Confidence Intervals 95% C. I., value, lower, upper). Altogether 100 atopic dermatitis patients were examined. We confirmed significant relationship between the results of specific IgE to allergen reagents (molecular components) of fish and the results open exposure test/history; the sensitivity is in the range of 33.3% (7.49%–70.07%)–44.4% (13.7%–78.80%). We did not confirm the significant relationship between the results of specific IgE to allergen reagents (molecular components) of shrimps and the results open exposure test/history; the sensitivity is in the range of 0%–40% (5.27%–85.34%). |
| first_indexed | 2024-04-11T20:41:26Z |
| format | Article |
| id | doaj.art-2789bd85af144054bcd740157497b80e |
| institution | Directory Open Access Journal |
| issn | 0954-0105 1465-3443 |
| language | English |
| last_indexed | 2024-04-11T20:41:26Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Food and Agricultural Immunology |
| spelling | doaj.art-2789bd85af144054bcd740157497b80e2022-12-22T04:04:12ZengTaylor & Francis GroupFood and Agricultural Immunology0954-01051465-34432022-12-0133111910.1080/09540105.2021.20055462005546ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitisJ. Čelakovská0E. Čermákova1R. Vaňková2C. Andrýs3J. Krejsek4Department of Dermatology and Venereology Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech RepublicDepartment of Medical Biophysic, Medical Faculty of Charles University, Hradec Králové, Czech republicDepartment of Clinical Immunology and Allergy, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech RepublicDepartment of Clinical Immunology and Allergy, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech RepublicDepartment of Clinical Immunology and Allergy, Faculty Hospital and Medical Faculty of Charles University, Hradec Králové, Czech RepublicThe sensitivity of ALEX2 Allergy Explorer test in patients suffering from atopic dermatitis and clinical reactions to fish/shrimps was evaluated. We compared the results of specific IgE to allergen reagents (molecular components) and clinical reactions in the open exposure test (patient’s history); the sensitivity was calculated with Fisher's Exact test (Rates and Confidence Intervals 95% C. I., value, lower, upper). Altogether 100 atopic dermatitis patients were examined. We confirmed significant relationship between the results of specific IgE to allergen reagents (molecular components) of fish and the results open exposure test/history; the sensitivity is in the range of 33.3% (7.49%–70.07%)–44.4% (13.7%–78.80%). We did not confirm the significant relationship between the results of specific IgE to allergen reagents (molecular components) of shrimps and the results open exposure test/history; the sensitivity is in the range of 0%–40% (5.27%–85.34%).http://dx.doi.org/10.1080/09540105.2021.2005546fish/shrimp allergyalex2 allergy exploreratopic dermatitisspecific ige |
| spellingShingle | J. Čelakovská E. Čermákova R. Vaňková C. Andrýs J. Krejsek ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis Food and Agricultural Immunology fish/shrimp allergy alex2 allergy explorer atopic dermatitis specific ige |
| title | ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis |
| title_full | ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis |
| title_fullStr | ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis |
| title_full_unstemmed | ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis |
| title_short | ALEX2 multiplex examination – results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis |
| title_sort | alex2 multiplex examination results of specific ige to fish and shrimps in patients suffering from atopic dermatitis |
| topic | fish/shrimp allergy alex2 allergy explorer atopic dermatitis specific ige |
| url | http://dx.doi.org/10.1080/09540105.2021.2005546 |
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