Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report

Strongyloides stercoralis is a nematode that is characterized by causing a usually asymptomatic intestinal infection in immunocompetent individuals. However, in patients living with HIV and depending on their immune status, it can generate a hyperinfection syndrome with various complications due to...

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Main Authors: Urbano-Albán, Diana Carolina, Orozco-Burbano, Juan David, Andrade-Eraso, Andrés Felipe, Cabrera-Velasco, Carlos Ernesto, Lozano-Fernández, Víctor Hugo
Format: Article
Language:Spanish
Published: Universidad de Antioquia 2022-10-01
Series:Iatreia
Subjects:
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author Urbano-Albán, Diana Carolina
Orozco-Burbano, Juan David
Andrade-Eraso, Andrés Felipe
Cabrera-Velasco, Carlos Ernesto
Lozano-Fernández, Víctor Hugo
author_facet Urbano-Albán, Diana Carolina
Orozco-Burbano, Juan David
Andrade-Eraso, Andrés Felipe
Cabrera-Velasco, Carlos Ernesto
Lozano-Fernández, Víctor Hugo
author_sort Urbano-Albán, Diana Carolina
collection DOAJ
description Strongyloides stercoralis is a nematode that is characterized by causing a usually asymptomatic intestinal infection in immunocompetent individuals. However, in patients living with HIV and depending on their immune status, it can generate a hyperinfection syndrome with various complications due to dissemination to different organs. We present the case of a 30-year-old patient with a de novo diagnosis of human immunodeficiency virus infection and lymphoproliferative disease. Within the laboratory workup, the presence of Strongyloides stercoralis was documented in the bone marrow. Despite having a CD4+ T lymphocyte count greater than 400 cells/microliter and having started treatment for this condition with ivermectin, the patient died due to a septic state associated with hyperinfection syndrome, which is why this is considered an unusual case that alerts the clinician to take into account the presence of the nematode in patients living with HIV.
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spelling doaj.art-278a67f1d2c04629ba37cf5e023963f62022-12-22T03:55:03ZspaUniversidad de AntioquiaIatreia0121-07932011-79652022-10-0135447547910.17533/udea.iatreia.178Strongyloides stercoralis in the bone marrow of a person living with HIV: Case reportUrbano-Albán, Diana Carolina0Orozco-Burbano, Juan David1Andrade-Eraso, Andrés Felipe 2Cabrera-Velasco, Carlos Ernesto 3Lozano-Fernández, Víctor Hugo 4Hospital Universitario San José, Popayán, ColombiaHospital Universitario San José, Popayán, ColombiaHospital Universitario San José, Popayán, ColombiaHospital Universitario San José, Popayán, ColombiaHospital Universitario San José, Popayán, ColombiaStrongyloides stercoralis is a nematode that is characterized by causing a usually asymptomatic intestinal infection in immunocompetent individuals. However, in patients living with HIV and depending on their immune status, it can generate a hyperinfection syndrome with various complications due to dissemination to different organs. We present the case of a 30-year-old patient with a de novo diagnosis of human immunodeficiency virus infection and lymphoproliferative disease. Within the laboratory workup, the presence of Strongyloides stercoralis was documented in the bone marrow. Despite having a CD4+ T lymphocyte count greater than 400 cells/microliter and having started treatment for this condition with ivermectin, the patient died due to a septic state associated with hyperinfection syndrome, which is why this is considered an unusual case that alerts the clinician to take into account the presence of the nematode in patients living with HIV.immune reconstitution inflammatory syndromestrongyloides stercoralisstrongyloidiasis
spellingShingle Urbano-Albán, Diana Carolina
Orozco-Burbano, Juan David
Andrade-Eraso, Andrés Felipe
Cabrera-Velasco, Carlos Ernesto
Lozano-Fernández, Víctor Hugo
Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
Iatreia
immune reconstitution inflammatory syndrome
strongyloides stercoralis
strongyloidiasis
title Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
title_full Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
title_fullStr Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
title_full_unstemmed Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
title_short Strongyloides stercoralis in the bone marrow of a person living with HIV: Case report
title_sort strongyloides stercoralis in the bone marrow of a person living with hiv case report
topic immune reconstitution inflammatory syndrome
strongyloides stercoralis
strongyloidiasis
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