Rain drop pigmentation in chronic arsenic poisoning

Contamination of ground water with arsenic is a problem being faced by over 30 countries in the world, since a few decades. Arsenicosis is a multisystem disorder characterised by cutaneous, gastrointestinal, urological and hematological manifestations. The WHO defines arsenicosis as a chronic health...

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Bibliographic Details
Main Authors: Anupam Das, Anand Toshniwal, Kunal Majumdar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Pigment International
Subjects:
Online Access:http://www.pigmentinternational.com/article.asp?issn=2349-5847;year=2020;volume=7;issue=1;spage=61;epage=62;aulast=Das
Description
Summary:Contamination of ground water with arsenic is a problem being faced by over 30 countries in the world, since a few decades. Arsenicosis is a multisystem disorder characterised by cutaneous, gastrointestinal, urological and hematological manifestations. The WHO defines arsenicosis as a chronic health condition arising from prolonged ingestion (not less than 6 months) of arsenic above a safe dose, usually manifested by characteristic skin lesions, with or without involvement of internal organs. The WHO guideline for arsenic in drinking water is 0.01mg/ml. Cutaneous lesions are the earliest manifestations characterised by mottled pigmentation of covered areas of body called as rain drop pigmentation, blotchy mucosal pigmentation, depigmentation, palmoplantar pitting and keratosis.[1] Cutaneous malignancies which can be caused by arsenicosis include bowens disease, squamous cell carcinoma, basal cell carcinoma and melanoma.[2] It can also cause ischemic heart disease, hepatosplenomegaly, black foot disease and internal malignancies. [3]
ISSN:2349-5847
2349-5782