Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis
Introduction: Allergic rhinitis is a common chronic allergic disease. The effects of allergic diseases on autoimmune diseases are not known. The patients are predisposed to react to exogenic antigens in allergic diseases and they can more easily react to endogenous antigens. Therefore, autoantibody...
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Galenos Yayinevi
2017-09-01
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| Series: | İstanbul Medical Journal |
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http://imj.galenos.com.tr/archives/archive-detail/article-preview/evaluating-of-thyroid-function-tests-and-thyroid-a/20488
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| _version_ | 1797909946361184256 |
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| author | Feridun Gürlek Eyyüp Taşdemir |
| author_facet | Feridun Gürlek Eyyüp Taşdemir |
| author_sort | Feridun Gürlek |
| collection | DOAJ |
| description | Introduction: Allergic rhinitis is a common chronic allergic disease. The effects of allergic diseases on autoimmune diseases are not known. The patients are predisposed to react to exogenic antigens in allergic diseases and they can more easily react to endogenous antigens. Therefore, autoantibody prevalence studies are required. In this study, we attempted to prove the possible relation between the thyroid function tests, thyroid autoantibodies and allergic rhinitis.Methods: A total of 319 patients, with 193 (60%) with allergic rhinitis between June 2015 and October 2015 and 126 (40%) as the control group were included in the study; 38% of the patient group was male and 62% was female; and 44% of the control group was male and 56% was female.Results: No significant difference was found in the antithyroglobuline (anti-Tg; p=0.295) and antithyroid peroxidase (anti-TPO; p=0.224) and thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) (p>0.05) values between the patient and control groups. In our study, autoantibody positivity ratios in the patients with allergic rhinitis were specified as 15.6% (anti-Tg) and 11.5% (anti-TPO). In addition, a weak positive relationship was found between the age and anti-Tg values (p<0.001; r=0.268).Conclusion: Allergic and autoimmune diseases together find are not common phenomena in an individual. This can be explained to usually managed by different processing of the Th1 and Th2 pathways. Although we did not find a statistical significance in our study, the thyroid autoantibodies were higher in the allergic rhinitis group with compared to controls . We believe that these patients should be closely monitored in terms of clinical and laboratory parameters and should be followed in terms of thyroid disease development. |
| first_indexed | 2024-04-10T11:16:28Z |
| format | Article |
| id | doaj.art-278ace8f377d41cdad4b67935b8209b8 |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T11:16:28Z |
| publishDate | 2017-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-278ace8f377d41cdad4b67935b8209b82023-02-15T16:18:50ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2017-09-0118313914410.5152/imj.2017.9091213049054Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic RhinitisFeridun Gürlek0Eyyüp Taşdemir1 Department of Allergy and Immunology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey Department of Internal Diseases, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey Introduction: Allergic rhinitis is a common chronic allergic disease. The effects of allergic diseases on autoimmune diseases are not known. The patients are predisposed to react to exogenic antigens in allergic diseases and they can more easily react to endogenous antigens. Therefore, autoantibody prevalence studies are required. In this study, we attempted to prove the possible relation between the thyroid function tests, thyroid autoantibodies and allergic rhinitis.Methods: A total of 319 patients, with 193 (60%) with allergic rhinitis between June 2015 and October 2015 and 126 (40%) as the control group were included in the study; 38% of the patient group was male and 62% was female; and 44% of the control group was male and 56% was female.Results: No significant difference was found in the antithyroglobuline (anti-Tg; p=0.295) and antithyroid peroxidase (anti-TPO; p=0.224) and thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) (p>0.05) values between the patient and control groups. In our study, autoantibody positivity ratios in the patients with allergic rhinitis were specified as 15.6% (anti-Tg) and 11.5% (anti-TPO). In addition, a weak positive relationship was found between the age and anti-Tg values (p<0.001; r=0.268).Conclusion: Allergic and autoimmune diseases together find are not common phenomena in an individual. This can be explained to usually managed by different processing of the Th1 and Th2 pathways. Although we did not find a statistical significance in our study, the thyroid autoantibodies were higher in the allergic rhinitis group with compared to controls . We believe that these patients should be closely monitored in terms of clinical and laboratory parameters and should be followed in terms of thyroid disease development. http://imj.galenos.com.tr/archives/archive-detail/article-preview/evaluating-of-thyroid-function-tests-and-thyroid-a/20488 Allergic rhinitisthyroidautoantibody |
| spellingShingle | Feridun Gürlek Eyyüp Taşdemir Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis İstanbul Medical Journal Allergic rhinitis thyroid autoantibody |
| title | Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis |
| title_full | Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis |
| title_fullStr | Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis |
| title_full_unstemmed | Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis |
| title_short | Evaluating of Thyroid Function Tests and Thyroid Autoantibodies in Patients with Allergic Rhinitis |
| title_sort | evaluating of thyroid function tests and thyroid autoantibodies in patients with allergic rhinitis |
| topic | Allergic rhinitis thyroid autoantibody |
| url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/evaluating-of-thyroid-function-tests-and-thyroid-a/20488
|
| work_keys_str_mv | AT feridungurlek evaluatingofthyroidfunctiontestsandthyroidautoantibodiesinpatientswithallergicrhinitis AT eyyuptasdemir evaluatingofthyroidfunctiontestsandthyroidautoantibodiesinpatientswithallergicrhinitis |