Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks
This experiment was conducted to investigate the effects of methionine analogues 2-hydroxy-4-methylthio butanoic acid isopropyl ester (HBMi) on growth performance, nutrient apparent digestibility, serum metabolite, serum free amino acids, and rumen fermentation parameters of yaks. Twenty-four male M...
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MDPI AG
2022-11-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/22/3175 |
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| author | Xirui Zhang Zizhen Zuo Yao Liu Chenxi Wang Zhongli Peng Jincheng Zhong Ming Zhang Haibo Wang |
| author_facet | Xirui Zhang Zizhen Zuo Yao Liu Chenxi Wang Zhongli Peng Jincheng Zhong Ming Zhang Haibo Wang |
| author_sort | Xirui Zhang |
| collection | DOAJ |
| description | This experiment was conducted to investigate the effects of methionine analogues 2-hydroxy-4-methylthio butanoic acid isopropyl ester (HBMi) on growth performance, nutrient apparent digestibility, serum metabolite, serum free amino acids, and rumen fermentation parameters of yaks. Twenty-four male Maiwa yaks (252.79 ± 15.95 kg) were randomly allocated to four dietary treatments: basic diet (CON), or three HBMi (MetaSmart (MS); Adisseo Inc., Antony, France) supplementation treatments: MS1 (5 g), MS2 (10 g), and MS3 (15 g). The results showed that the increase in the supplemented MS levels linearly increased the average daily gain (<i>p</i> < 0.05), while the serum alkaline phosphatase activity and malondialdehyde content were increased when yaks were fed with 15 g/d MS (<i>p</i> < 0.05). The diet supplemented with MS linearly increased the percentages of glutamic acid and proline, and linearly or quadratically decreased the percentages of isoleucine, phenylalanine, and valine (<i>p</i> < 0.05). Furthermore, supplementation of 10 g/d and 15 g/d MS increased ruminal microbial crude protein (<i>p</i> < 0.05). The ratio of acetate to propionate in the MS2 group was lower than those in CON and MS1 groups (<i>p</i> < 0.05). In summary, a diet supplemented with 10 g/d MS could be an effective way to improve the growth performance of fattening yaks without negative effects. |
| first_indexed | 2024-03-09T18:31:00Z |
| format | Article |
| id | doaj.art-278b3a3d62e2425993c035993b28ece1 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T18:31:00Z |
| publishDate | 2022-11-01 |
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| record_format | Article |
| series | Animals |
| spelling | doaj.art-278b3a3d62e2425993c035993b28ece12023-11-24T07:29:28ZengMDPI AGAnimals2076-26152022-11-011222317510.3390/ani12223175Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of YaksXirui Zhang0Zizhen Zuo1Yao Liu2Chenxi Wang3Zhongli Peng4Jincheng Zhong5Ming Zhang6Haibo Wang7College of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, ChinaKey Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu 610041, ChinaCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, ChinaCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, ChinaCollege of Animal and Veterinary Sciences, Southwest Minzu University, Chengdu 610041, ChinaKey Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu 610041, ChinaKey Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu 610041, ChinaKey Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu 610041, ChinaThis experiment was conducted to investigate the effects of methionine analogues 2-hydroxy-4-methylthio butanoic acid isopropyl ester (HBMi) on growth performance, nutrient apparent digestibility, serum metabolite, serum free amino acids, and rumen fermentation parameters of yaks. Twenty-four male Maiwa yaks (252.79 ± 15.95 kg) were randomly allocated to four dietary treatments: basic diet (CON), or three HBMi (MetaSmart (MS); Adisseo Inc., Antony, France) supplementation treatments: MS1 (5 g), MS2 (10 g), and MS3 (15 g). The results showed that the increase in the supplemented MS levels linearly increased the average daily gain (<i>p</i> < 0.05), while the serum alkaline phosphatase activity and malondialdehyde content were increased when yaks were fed with 15 g/d MS (<i>p</i> < 0.05). The diet supplemented with MS linearly increased the percentages of glutamic acid and proline, and linearly or quadratically decreased the percentages of isoleucine, phenylalanine, and valine (<i>p</i> < 0.05). Furthermore, supplementation of 10 g/d and 15 g/d MS increased ruminal microbial crude protein (<i>p</i> < 0.05). The ratio of acetate to propionate in the MS2 group was lower than those in CON and MS1 groups (<i>p</i> < 0.05). In summary, a diet supplemented with 10 g/d MS could be an effective way to improve the growth performance of fattening yaks without negative effects.https://www.mdpi.com/2076-2615/12/22/3175yakmethionine analoguesserum metabolitefree amino acidruminal fermentation |
| spellingShingle | Xirui Zhang Zizhen Zuo Yao Liu Chenxi Wang Zhongli Peng Jincheng Zhong Ming Zhang Haibo Wang Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks Animals yak methionine analogues serum metabolite free amino acid ruminal fermentation |
| title | Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks |
| title_full | Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks |
| title_fullStr | Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks |
| title_full_unstemmed | Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks |
| title_short | Effect of Methionine Analogues on Growth Performance, Serum Biochemical Parameters, Serum Free Amino Acids and Rumen Fermentation of Yaks |
| title_sort | effect of methionine analogues on growth performance serum biochemical parameters serum free amino acids and rumen fermentation of yaks |
| topic | yak methionine analogues serum metabolite free amino acid ruminal fermentation |
| url | https://www.mdpi.com/2076-2615/12/22/3175 |
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