Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations)
We present two clinical cases: the first patient had combination of antiphospholipid syndrome (APS) and melanoma, and the second – systemic lupus erythematosus (SLE) and APS, melanoma, infiltrative tuberculosis and Herpes zoster. Managing patients with SLE combined with APS is really challenging. In...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2021-08-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1176 |
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| author | A. A. Shumilova T. M. Reshetnyak F. A. Cheldieva A. M. Lila |
| author_facet | A. A. Shumilova T. M. Reshetnyak F. A. Cheldieva A. M. Lila |
| author_sort | A. A. Shumilova |
| collection | DOAJ |
| description | We present two clinical cases: the first patient had combination of antiphospholipid syndrome (APS) and melanoma, and the second – systemic lupus erythematosus (SLE) and APS, melanoma, infiltrative tuberculosis and Herpes zoster. Managing patients with SLE combined with APS is really challenging. Infections and malignant neoplasms, along with kidney damage and cardiovascular diseases, are a significant cause of death in this cohort of patients. The role of antibodies to phospholipids in the onset of malignancy is still under discussion. The combination of rheumatic diseases with oncological or infectious pathology complicates therapy, limiting the use of drugs, recommended by clinical guidelines. |
| first_indexed | 2024-04-10T02:06:06Z |
| format | Article |
| id | doaj.art-278de196a0d24a5d9310c8c6ea0f61b4 |
| institution | Directory Open Access Journal |
| issn | 1996-7012 2310-158X |
| language | Russian |
| last_indexed | 2025-03-14T08:18:52Z |
| publishDate | 2021-08-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj.art-278de196a0d24a5d9310c8c6ea0f61b42025-03-02T13:11:05ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-08-01154879310.14412/1996-7012-2021-4-87-932386Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations)A. A. Shumilova0T. M. Reshetnyak1F. A. Cheldieva2A. M. Lila3V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional EducationV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional EducationV.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuing Professional EducationWe present two clinical cases: the first patient had combination of antiphospholipid syndrome (APS) and melanoma, and the second – systemic lupus erythematosus (SLE) and APS, melanoma, infiltrative tuberculosis and Herpes zoster. Managing patients with SLE combined with APS is really challenging. Infections and malignant neoplasms, along with kidney damage and cardiovascular diseases, are a significant cause of death in this cohort of patients. The role of antibodies to phospholipids in the onset of malignancy is still under discussion. The combination of rheumatic diseases with oncological or infectious pathology complicates therapy, limiting the use of drugs, recommended by clinical guidelines.https://mrj.ima-press.net/mrj/article/view/1176antiphospholipid syndromesystemic lupus erythematosusmelanomapulmonary tuberculosisclinical observations |
| spellingShingle | A. A. Shumilova T. M. Reshetnyak F. A. Cheldieva A. M. Lila Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) Современная ревматология antiphospholipid syndrome systemic lupus erythematosus melanoma pulmonary tuberculosis clinical observations |
| title | Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) |
| title_full | Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) |
| title_fullStr | Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) |
| title_full_unstemmed | Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) |
| title_short | Difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis (clinical observations) |
| title_sort | difficulties in management of patients with systemic lupus erythematosus and antiphospholipid syndrome in combination with melanoma and infiltrative tuberculosis clinical observations |
| topic | antiphospholipid syndrome systemic lupus erythematosus melanoma pulmonary tuberculosis clinical observations |
| url | https://mrj.ima-press.net/mrj/article/view/1176 |
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