Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors

      So much studies done to present the diabetic neuropathic changes of the peripheral nerves but most of them were done experimentally on laboratory animals , but little about human diabetic neuropathic and structural changes specially of large nerves like common peroneal and tibial nerve .Accor...

Full description

Bibliographic Details
Main Authors: Payman Jamal Muhamad Ameen, Talib Jawad Kathum, Hewa Baker
Format: Article
Language:English
Published: College of medicine/ University of Diyala 2019-11-01
Series:Diyala Journal of Medicine
Subjects:
Online Access:http://djm.uodiyala.edu.iq/index.php/djm/article/view/467
_version_ 1797454817015103488
author Payman Jamal Muhamad Ameen
Talib Jawad Kathum
Hewa Baker
author_facet Payman Jamal Muhamad Ameen
Talib Jawad Kathum
Hewa Baker
author_sort Payman Jamal Muhamad Ameen
collection DOAJ
description       So much studies done to present the diabetic neuropathic changes of the peripheral nerves but most of them were done experimentally on laboratory animals , but little about human diabetic neuropathic and structural changes specially of large nerves like common peroneal and tibial nerve .Accordingly the present work designed to study the neuropathic changes of the tibial and common peroneal nerve samples, taken from amputated legs of 30 diabetic patients (8 females and 22 males) at age ranging between (55-75) years, and from 30 cadavers (4 females and 26 males) at age ranging between (25-50) years as control group. The teased and osmicated tibial and common peroneal nerve fibers, and histological sections taken from diabetic patients showed different deformity and Morphometrical changes, of that ; paranodal swelling, segmental demyelination, some areas with an areas of un even myelin and shortest segmentation the (common peroneal nerve 22µ and tibial nerve 265µ ) in comparison to the control group. The multiple regression analysis, showed significant effect of age of the patient and duration of diabetes on the neuropathic changes.
first_indexed 2024-03-09T15:42:35Z
format Article
id doaj.art-278f18ef3f654200a3b17bd442ace7b8
institution Directory Open Access Journal
issn 2219-9764
2617-8982
language English
last_indexed 2024-03-09T15:42:35Z
publishDate 2019-11-01
publisher College of medicine/ University of Diyala
record_format Article
series Diyala Journal of Medicine
spelling doaj.art-278f18ef3f654200a3b17bd442ace7b82023-11-24T23:23:22ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822019-11-0112Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk FactorsPayman Jamal Muhamad Ameen Talib Jawad KathumHewa Baker       So much studies done to present the diabetic neuropathic changes of the peripheral nerves but most of them were done experimentally on laboratory animals , but little about human diabetic neuropathic and structural changes specially of large nerves like common peroneal and tibial nerve .Accordingly the present work designed to study the neuropathic changes of the tibial and common peroneal nerve samples, taken from amputated legs of 30 diabetic patients (8 females and 22 males) at age ranging between (55-75) years, and from 30 cadavers (4 females and 26 males) at age ranging between (25-50) years as control group. The teased and osmicated tibial and common peroneal nerve fibers, and histological sections taken from diabetic patients showed different deformity and Morphometrical changes, of that ; paranodal swelling, segmental demyelination, some areas with an areas of un even myelin and shortest segmentation the (common peroneal nerve 22µ and tibial nerve 265µ ) in comparison to the control group. The multiple regression analysis, showed significant effect of age of the patient and duration of diabetes on the neuropathic changes. http://djm.uodiyala.edu.iq/index.php/djm/article/view/467Neuropathic , Tibial Nerve , Risk Factors
spellingShingle Payman Jamal Muhamad Ameen
Talib Jawad Kathum
Hewa Baker
Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
Diyala Journal of Medicine
Neuropathic , Tibial Nerve , Risk Factors
title Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
title_full Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
title_fullStr Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
title_full_unstemmed Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
title_short Neuropathic Changes of Osmicated Common Peroneal and Tibial Nerve in Diabetic Patients and the Related Risk Factors
title_sort neuropathic changes of osmicated common peroneal and tibial nerve in diabetic patients and the related risk factors
topic Neuropathic , Tibial Nerve , Risk Factors
url http://djm.uodiyala.edu.iq/index.php/djm/article/view/467
work_keys_str_mv AT paymanjamalmuhamadameen neuropathicchangesofosmicatedcommonperonealandtibialnerveindiabeticpatientsandtherelatedriskfactors
AT talibjawadkathum neuropathicchangesofosmicatedcommonperonealandtibialnerveindiabeticpatientsandtherelatedriskfactors
AT hewabaker neuropathicchangesofosmicatedcommonperonealandtibialnerveindiabeticpatientsandtherelatedriskfactors