ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT
Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding this possible complication after dental implant...
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Romanian Society of Oral Rehabilitation
2022-08-01
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Series: | Romanian Journal of Oral Rehabilitation |
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Online Access: | https://www.rjor.ro/alpha-tumor-necrosis-as-predictive-factor-in-dental-implant-management/ |
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author | Marcel-Lucian Dobresu Aureliana Caraiane Gheorghe Raftu Nicolae Chele Ion Dabija Dumitru Chele Florin Ciprian Badea Victoria Badea |
author_facet | Marcel-Lucian Dobresu Aureliana Caraiane Gheorghe Raftu Nicolae Chele Ion Dabija Dumitru Chele Florin Ciprian Badea Victoria Badea |
author_sort | Marcel-Lucian Dobresu |
collection | DOAJ |
description | Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding this possible complication after dental implant insertion.
Material and methods. The study group included 54 patients who were evaluated clinically and paraclinically seven days after the insertion of dental implants and divided into three groups: with a favorable evolution, mucositis and peri-implantitis. After the clinical examination, samples of peri-implant fluid were collected to determine the values of TNF-alpha. Results. There is a direct proportional relationship between TNF-alpha values and clinically parameters; also, there are difference with high statistical significance between TNF-alpha values identified in the three groups of patients. Conclusions. The is a strong relationship between the levels of TNF-alpha and clinically parameters in patients with favorable evolution, mucositis and peri-implantitis. Understanding the role of proinflammatory citokines as TNF-alpha in the etiopathogenesis of peri-implantitis is essential in developing strategies for the prevention, diagnosis and treatment of this disese. |
first_indexed | 2024-04-10T07:10:18Z |
format | Article |
id | doaj.art-279320b183674974933bbb528fc0a9df |
institution | Directory Open Access Journal |
issn | 2066-7000 2601-4661 |
language | English |
last_indexed | 2024-04-10T07:10:18Z |
publishDate | 2022-08-01 |
publisher | Romanian Society of Oral Rehabilitation |
record_format | Article |
series | Romanian Journal of Oral Rehabilitation |
spelling | doaj.art-279320b183674974933bbb528fc0a9df2023-02-26T13:51:55ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612022-08-011439195ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENTMarcel-Lucian Dobresu0Aureliana Caraiane1Gheorghe Raftu2Nicolae Chele3Ion Dabija4Dumitru Chele5Florin Ciprian Badea6Victoria Badea7 “Ovidius” University of Constanta, Romania, Faculty of Dental Medicine, Department of Dentistry“Ovidius” University of Constanta, Romania, Faculty of Dental Medicine, Department of Dentistry“Ovidius” University of Constanta, Romania, Faculty of Dental Medicine, Department of DentistryNicolae Testemitsanu” University of Medicine and Pharmacy of Chisinau, Republic of Moldova, Faculty of Dental Medicine “Arsenie Gutan“, Deparment of Oro-Maxillofacial Surgery and Oral ImplantologyNicolae Testemitsanu” University of Medicine and Pharmacy of Chisinau, Republic of Moldova, Faculty of Dental Medicine “Arsenie Gutan“, Deparment of Oro-Maxillofacial Surgery and Oral ImplantologyNicolae Testemitsanu” University of Medicine and Pharmacy of Chisinau, Republic of Moldova, Faculty of Dental Medicine “Arsenie Gutan“, Deparment of Oro-Maxillofacial Surgery and Oral Implantology “Ovidius” University of Constanta, Romania, Faculty of Dental Medicine, Department of Dentistry“Ovidius” University of Constanta, Romania, Faculty of Dental Medicine, Department of DentistryIntroduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding this possible complication after dental implant insertion. Material and methods. The study group included 54 patients who were evaluated clinically and paraclinically seven days after the insertion of dental implants and divided into three groups: with a favorable evolution, mucositis and peri-implantitis. After the clinical examination, samples of peri-implant fluid were collected to determine the values of TNF-alpha. Results. There is a direct proportional relationship between TNF-alpha values and clinically parameters; also, there are difference with high statistical significance between TNF-alpha values identified in the three groups of patients. Conclusions. The is a strong relationship between the levels of TNF-alpha and clinically parameters in patients with favorable evolution, mucositis and peri-implantitis. Understanding the role of proinflammatory citokines as TNF-alpha in the etiopathogenesis of peri-implantitis is essential in developing strategies for the prevention, diagnosis and treatment of this disese.https://www.rjor.ro/alpha-tumor-necrosis-as-predictive-factor-in-dental-implant-management/tnf-alphaperi-implantitis markerdental implant management |
spellingShingle | Marcel-Lucian Dobresu Aureliana Caraiane Gheorghe Raftu Nicolae Chele Ion Dabija Dumitru Chele Florin Ciprian Badea Victoria Badea ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT Romanian Journal of Oral Rehabilitation tnf-alpha peri-implantitis marker dental implant management |
title | ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT |
title_full | ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT |
title_fullStr | ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT |
title_full_unstemmed | ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT |
title_short | ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT |
title_sort | alpha tumor necrosis as predictive factor in dental implant management |
topic | tnf-alpha peri-implantitis marker dental implant management |
url | https://www.rjor.ro/alpha-tumor-necrosis-as-predictive-factor-in-dental-implant-management/ |
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