Artificial microbial consortia for bioproduction processes
Abstract The application of artificial microbial consortia for biotechnological production processes is an emerging field in research as it offers great potential for the improvement of established as well as the development of novel processes. In this review, we summarize recent highlights in the u...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2023-01-01
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| Series: | Engineering in Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/elsc.202100152 |
| _version_ | 1797961261438205952 |
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| author | Fabian Mittermeier Miriam Bäumler Prasika Arulrajah José de Jesús García Lima Sebastian Hauke Anna Stock Dirk Weuster‐Botz |
| author_facet | Fabian Mittermeier Miriam Bäumler Prasika Arulrajah José de Jesús García Lima Sebastian Hauke Anna Stock Dirk Weuster‐Botz |
| author_sort | Fabian Mittermeier |
| collection | DOAJ |
| description | Abstract The application of artificial microbial consortia for biotechnological production processes is an emerging field in research as it offers great potential for the improvement of established as well as the development of novel processes. In this review, we summarize recent highlights in the usage of various microbial consortia for the production of, for example, platform chemicals, biofuels, or pharmaceutical compounds. It aims to demonstrate the great potential of co‐cultures by employing different organisms and interaction mechanisms and exploiting their respective advantages. Bacteria and yeasts often offer a broad spectrum of possible products, fungi enable the utilization of complex lignocellulosic substrates via enzyme secretion and hydrolysis, and microalgae can feature their abilities to fixate CO2 through photosynthesis for other organisms as well as to form lipids as potential fuelstocks. However, the complexity of interactions between microbes require methods for observing population dynamics within the process and modern approaches such as modeling or automation for process development. After shortly discussing these interaction mechanisms, we aim to present a broad variety of successfully established co‐culture processes to display the potential of artificial microbial consortia for the production of biotechnological products. |
| first_indexed | 2024-04-11T00:56:14Z |
| format | Article |
| id | doaj.art-27938c14cf6f4a5296a4d8bd37d2dbab |
| institution | Directory Open Access Journal |
| issn | 1618-0240 1618-2863 |
| language | English |
| last_indexed | 2024-04-11T00:56:14Z |
| publishDate | 2023-01-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Engineering in Life Sciences |
| spelling | doaj.art-27938c14cf6f4a5296a4d8bd37d2dbab2023-01-05T02:40:22ZengWiley-VCHEngineering in Life Sciences1618-02401618-28632023-01-01231n/an/a10.1002/elsc.202100152Artificial microbial consortia for bioproduction processesFabian Mittermeier0Miriam Bäumler1Prasika Arulrajah2José de Jesús García Lima3Sebastian Hauke4Anna Stock5Dirk Weuster‐Botz6Department of Energy and Process Engineering TUM School of Engineering and Design Chair of Biochemical Engineering Technical University of Munich Garching GermanyDepartment of Energy and Process Engineering TUM School of Engineering and Design Chair of Biochemical Engineering Technical University of Munich Garching GermanyTUM School of Engineering and Design Technical University of Munich Garching GermanyTUM School of Engineering and Design Technical University of Munich Garching GermanyTUM School of Engineering and Design Technical University of Munich Garching GermanyTUM School of Engineering and Design Technical University of Munich Garching GermanyDepartment of Energy and Process Engineering TUM School of Engineering and Design Chair of Biochemical Engineering Technical University of Munich Garching GermanyAbstract The application of artificial microbial consortia for biotechnological production processes is an emerging field in research as it offers great potential for the improvement of established as well as the development of novel processes. In this review, we summarize recent highlights in the usage of various microbial consortia for the production of, for example, platform chemicals, biofuels, or pharmaceutical compounds. It aims to demonstrate the great potential of co‐cultures by employing different organisms and interaction mechanisms and exploiting their respective advantages. Bacteria and yeasts often offer a broad spectrum of possible products, fungi enable the utilization of complex lignocellulosic substrates via enzyme secretion and hydrolysis, and microalgae can feature their abilities to fixate CO2 through photosynthesis for other organisms as well as to form lipids as potential fuelstocks. However, the complexity of interactions between microbes require methods for observing population dynamics within the process and modern approaches such as modeling or automation for process development. After shortly discussing these interaction mechanisms, we aim to present a broad variety of successfully established co‐culture processes to display the potential of artificial microbial consortia for the production of biotechnological products.https://doi.org/10.1002/elsc.202100152artificial consortiabioproduction processescell‐to‐cell interactionsco‐cultivation |
| spellingShingle | Fabian Mittermeier Miriam Bäumler Prasika Arulrajah José de Jesús García Lima Sebastian Hauke Anna Stock Dirk Weuster‐Botz Artificial microbial consortia for bioproduction processes Engineering in Life Sciences artificial consortia bioproduction processes cell‐to‐cell interactions co‐cultivation |
| title | Artificial microbial consortia for bioproduction processes |
| title_full | Artificial microbial consortia for bioproduction processes |
| title_fullStr | Artificial microbial consortia for bioproduction processes |
| title_full_unstemmed | Artificial microbial consortia for bioproduction processes |
| title_short | Artificial microbial consortia for bioproduction processes |
| title_sort | artificial microbial consortia for bioproduction processes |
| topic | artificial consortia bioproduction processes cell‐to‐cell interactions co‐cultivation |
| url | https://doi.org/10.1002/elsc.202100152 |
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