Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients
Ankylosing spondylitis is a complex debilitating disease because its pathogenesis is not clear. This study aims at detecting some pathogenesis factors that lead to induce the disease. Chlamydia pneumoniae is one of these pathogenesis factors which acts as a triggering factor for the disease. The stu...
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| Format: | Article |
| Language: | Arabic |
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College of Science for Women, University of Baghdad
2018-03-01
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| Series: | Baghdad Science Journal |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2435 |
| _version_ | 1811327781900910592 |
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| author | Baghdad Science Journal |
| author_facet | Baghdad Science Journal |
| author_sort | Baghdad Science Journal |
| collection | DOAJ |
| description | Ankylosing spondylitis is a complex debilitating disease because its pathogenesis is not clear. This study aims at detecting some pathogenesis factors that lead to induce the disease. Chlamydia pneumoniae is one of these pathogenesis factors which acts as a triggering factor for the disease. The study groups included forty Iraqi Ankylosing spondylitis patients and forty healthy persons as a control group. Immunological and molecular examinations were done to detect Chlamydia. pneumoniae in AS group. The immunological results were performed by Enzyme-Linked Immunosorbent Assay (ELISA) to detect anti-IgG and anti-IgM antibodies of C. pneumoniae revealed that five of forty AS patients' samples (12.5%) were positive for anti-IgG and IgM C. pneumoniae antibodies compared to controls which revealed seronegative. Molecular detection included 16srRNA and HSP-70 genes were to ensure the serological examination for detection of bacteria in the five blood samples which were positive; therefore, these results improved that C. pneumoniae played a role in the pathogenesis of the disease |
| first_indexed | 2024-04-13T15:14:10Z |
| format | Article |
| id | doaj.art-2794431243ef4274b036d420666ee628 |
| institution | Directory Open Access Journal |
| issn | 2078-8665 2411-7986 |
| language | Arabic |
| last_indexed | 2024-04-13T15:14:10Z |
| publishDate | 2018-03-01 |
| publisher | College of Science for Women, University of Baghdad |
| record_format | Article |
| series | Baghdad Science Journal |
| spelling | doaj.art-2794431243ef4274b036d420666ee6282022-12-22T02:41:55ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862018-03-0115110.21123/bsj.15.1.22-25Detection of Chlamydia pneumoniae in Ankylosing Spondylitis PatientsBaghdad Science JournalAnkylosing spondylitis is a complex debilitating disease because its pathogenesis is not clear. This study aims at detecting some pathogenesis factors that lead to induce the disease. Chlamydia pneumoniae is one of these pathogenesis factors which acts as a triggering factor for the disease. The study groups included forty Iraqi Ankylosing spondylitis patients and forty healthy persons as a control group. Immunological and molecular examinations were done to detect Chlamydia. pneumoniae in AS group. The immunological results were performed by Enzyme-Linked Immunosorbent Assay (ELISA) to detect anti-IgG and anti-IgM antibodies of C. pneumoniae revealed that five of forty AS patients' samples (12.5%) were positive for anti-IgG and IgM C. pneumoniae antibodies compared to controls which revealed seronegative. Molecular detection included 16srRNA and HSP-70 genes were to ensure the serological examination for detection of bacteria in the five blood samples which were positive; therefore, these results improved that C. pneumoniae played a role in the pathogenesis of the diseasehttp://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2435Chlamydia pneumoniae, Ankylosing spondylitis, 16sRNA, HSP-70 |
| spellingShingle | Baghdad Science Journal Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients Baghdad Science Journal Chlamydia pneumoniae, Ankylosing spondylitis, 16sRNA, HSP-70 |
| title | Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients |
| title_full | Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients |
| title_fullStr | Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients |
| title_full_unstemmed | Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients |
| title_short | Detection of Chlamydia pneumoniae in Ankylosing Spondylitis Patients |
| title_sort | detection of chlamydia pneumoniae in ankylosing spondylitis patients |
| topic | Chlamydia pneumoniae, Ankylosing spondylitis, 16sRNA, HSP-70 |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2435 |
| work_keys_str_mv | AT baghdadsciencejournal detectionofchlamydiapneumoniaeinankylosingspondylitispatients |