The research progress in the interaction between Candida albicans and cancers
Candida albicans is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that C. albicans infection increases the host susceptibility to cancer such as oral, gastric, and colorectal cancer....
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.988734/full |
| _version_ | 1811265608574042112 |
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| author | Dalang Yu Zhiping Liu |
| author_facet | Dalang Yu Zhiping Liu |
| author_sort | Dalang Yu |
| collection | DOAJ |
| description | Candida albicans is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that C. albicans infection increases the host susceptibility to cancer such as oral, gastric, and colorectal cancer. Cancer and anti-cancer treatment may also affect the colonization of C. albicans. C. albicans may promote the development of cancer by damaging mucosal epithelium, inducing the production of carcinogens, triggering chronic inflammation including Th17 cell-mediated immune response. In this article, we aim to elaborate the interaction between C. albicans and cancers development and summarize the potential molecular mechanisms, so as to provide theoretical basis for prevention, diagnosis and treatment of cancers. |
| first_indexed | 2024-04-12T20:26:55Z |
| format | Article |
| id | doaj.art-27976ad1684a4381bd8418e15d64c38d |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-12T20:26:55Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-27976ad1684a4381bd8418e15d64c38d2022-12-22T03:17:51ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-09-011310.3389/fmicb.2022.988734988734The research progress in the interaction between Candida albicans and cancersDalang Yu0Zhiping Liu1School of Basic Medicine, Fuzhou Medical College of Nanchang University, Fuzhou, Jiangxi, ChinaSchool of Basic Medicine, Gannan Medical University, Ganzhou, Jiangxi, ChinaCandida albicans is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that C. albicans infection increases the host susceptibility to cancer such as oral, gastric, and colorectal cancer. Cancer and anti-cancer treatment may also affect the colonization of C. albicans. C. albicans may promote the development of cancer by damaging mucosal epithelium, inducing the production of carcinogens, triggering chronic inflammation including Th17 cell-mediated immune response. In this article, we aim to elaborate the interaction between C. albicans and cancers development and summarize the potential molecular mechanisms, so as to provide theoretical basis for prevention, diagnosis and treatment of cancers.https://www.frontiersin.org/articles/10.3389/fmicb.2022.988734/fullCandida albicanscancerinflammationinteractiontherapy |
| spellingShingle | Dalang Yu Zhiping Liu The research progress in the interaction between Candida albicans and cancers Frontiers in Microbiology Candida albicans cancer inflammation interaction therapy |
| title | The research progress in the interaction between Candida albicans and cancers |
| title_full | The research progress in the interaction between Candida albicans and cancers |
| title_fullStr | The research progress in the interaction between Candida albicans and cancers |
| title_full_unstemmed | The research progress in the interaction between Candida albicans and cancers |
| title_short | The research progress in the interaction between Candida albicans and cancers |
| title_sort | research progress in the interaction between candida albicans and cancers |
| topic | Candida albicans cancer inflammation interaction therapy |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.988734/full |
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