Interindividual Variability of Apixaban Plasma Concentrations: Influence of Clinical and Genetic Factors in a Real-Life Cohort of Atrial Fibrillation Patients

Interindividual Variability of Apixaban Plasma Concentrations: Influence of Clinical and Genetic Factors in a Real-Life Cohort of Atrial Fibrillation Patients

(1) Background: Prescribing apixaban for stroke prevention has significantly increased in patients with non-valvular atrial fibrillation (NVAF). The <i>ABCB<sub>1</sub></i> genotype can influence apixaban absorption and bioavailability. The aim of the present study was to ass...

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Main Authors: Adela-Nicoleta Roşian, Ştefan Horia Roşian, Bela Kiss, Maria Georgia Ştefan, Adrian Pavel Trifa, Camelia Diana Ober, Ovidiu Anchidin, Anca Dana Buzoianu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Genes
Subjects:
apixaban
<i>ABCB<sub>1</sub></i>
non-valvular atrial fibrillation
P-glycoprotein
Online Access:https://www.mdpi.com/2073-4425/11/4/438

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