Entrapment of a Cytotoxic Drug into the Crystal Structure of Calcite for Targeted Drug Delivery

Entrapment of a Cytotoxic Drug into the Crystal Structure of Calcite for Targeted Drug Delivery

Controlled drug release and targeted drug delivery can reduce systemic toxicity of chemotherapeutics by restricting drugs to the target organ and increasing the local concentration. As tumors and inflamed tissue are often surrounded by an acidic microenvironment, pH-responsive calcium carbonates (Ca...

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Bibliographic Details
Main Authors: Amina Vazda, Michael Pujari-Palmer, Wei Xia, Håkan Engqvist
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Materials
Subjects:
calcite
target drug delivery
pH-responsiveness
in vitro
MCF-7
Online Access:https://www.mdpi.com/1996-1944/14/22/6735

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