Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock

Shock in newborn infants has unique etiopathologic origins that require careful assessment to direct specific interventions. Early diagnosis is key to successful management. Unlike adults and pediatric patients, shock in newborn infants is often recognized in the uncompensated phase by the presence...

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Main Authors: Yogen Singh, Anup C. Katheria, Farha Vora
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2018.00002/full
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author Yogen Singh
Yogen Singh
Anup C. Katheria
Anup C. Katheria
Farha Vora
author_facet Yogen Singh
Yogen Singh
Anup C. Katheria
Anup C. Katheria
Farha Vora
author_sort Yogen Singh
collection DOAJ
description Shock in newborn infants has unique etiopathologic origins that require careful assessment to direct specific interventions. Early diagnosis is key to successful management. Unlike adults and pediatric patients, shock in newborn infants is often recognized in the uncompensated phase by the presence of hypotension, which may be too late. The routine methods of evaluation used in the adult and pediatric population are often invasive and less feasible. We aim to discuss the pathophysiology in shock in newborn infants, including the transitional changes at birth and unique features that contribute to the challenges in early identification. Special emphasis has been placed on bedside focused echocardiography/focused cardiac ultrasound, which can be used as an additional tool for early, neonatologist driven, ongoing evaluation and management. An approach to goal oriented management of shock has been described and how bed side functional echocardiography can help in making a logical choice of intervention (fluid therapy, inotropic therapy or vasopressor therapy) in infants with shock.
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spelling doaj.art-279d01eeec6b4c0da35ef21dda2d9d2b2022-12-21T23:28:46ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602018-01-01610.3389/fped.2018.00002334266Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal ShockYogen Singh0Yogen Singh1Anup C. Katheria2Anup C. Katheria3Farha Vora4Department of Pediatric Cardiology and Neonatal Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United KingdomUniversity of Cambridge Clinical School of Medicine, Cambridge, United KingdomDepartment of Neonatology, Sharp Mary Birch Hospital for Women & Newborns, San Diego, CA, United StatesDepartment of Neonatology, Loma Linda University School of Medicine, Loma Linda, CA, United StatesDepartment of Neonatology, Loma Linda University School of Medicine, Loma Linda, CA, United StatesShock in newborn infants has unique etiopathologic origins that require careful assessment to direct specific interventions. Early diagnosis is key to successful management. Unlike adults and pediatric patients, shock in newborn infants is often recognized in the uncompensated phase by the presence of hypotension, which may be too late. The routine methods of evaluation used in the adult and pediatric population are often invasive and less feasible. We aim to discuss the pathophysiology in shock in newborn infants, including the transitional changes at birth and unique features that contribute to the challenges in early identification. Special emphasis has been placed on bedside focused echocardiography/focused cardiac ultrasound, which can be used as an additional tool for early, neonatologist driven, ongoing evaluation and management. An approach to goal oriented management of shock has been described and how bed side functional echocardiography can help in making a logical choice of intervention (fluid therapy, inotropic therapy or vasopressor therapy) in infants with shock.http://journal.frontiersin.org/article/10.3389/fped.2018.00002/fullneonatal shockfunctional echocardiographycardiac outputtissue perfusionhemodynamic
spellingShingle Yogen Singh
Yogen Singh
Anup C. Katheria
Anup C. Katheria
Farha Vora
Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
Frontiers in Pediatrics
neonatal shock
functional echocardiography
cardiac output
tissue perfusion
hemodynamic
title Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
title_full Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
title_fullStr Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
title_full_unstemmed Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
title_short Advances in Diagnosis and Management of Hemodynamic Instability in Neonatal Shock
title_sort advances in diagnosis and management of hemodynamic instability in neonatal shock
topic neonatal shock
functional echocardiography
cardiac output
tissue perfusion
hemodynamic
url http://journal.frontiersin.org/article/10.3389/fped.2018.00002/full
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