Inhaled Exosomes Genetically Manipulated to Overexpress CD24 (EXO-CD24) as a Compassionate Use in Severe ARDS Patients

Inhaled Exosomes Genetically Manipulated to Overexpress CD24 (EXO-CD24) as a Compassionate Use in Severe ARDS Patients

Rationale: Acute respiratory distress syndrome (ARDS) is a major global health concern with a significant unmet need. EXO-CD24 is delivered via inhalation-reduced cytokines and chemokine secretion and lung injury in ARDS and improved survival in mice models of ARDS, influenza, and sepsis. Objectives...

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Bibliographic Details
Main Authors: Orr Green, Gil Shenberg, Roni Baruch, Lihi Argaman, Talya Levin, Ian Michelson, Ruthy Hadary, Boris Isakovich, Miri Golos, Reut Schwartz, Ronan MacLoughlin, Nimrod Adi, Nadir Arber, Shiran Shapira
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
exosomes
CD24
EXO-CD24
acute respiratory distress syndrome
ARDS
COVID-19
Online Access:https://www.mdpi.com/2227-9059/11/9/2523

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