Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery

AimsTo evaluate the clinical efficiency of on-table extubation (OTE) versus delayed extubation in patients aged over 60 years that underwent minimally invasive mitral or aortic valve replacement surgery and evaluate the factors associated with successful OTE implementation.MaterialsPatients over 60...

Full description

Bibliographic Details
Main Authors: Yunfen Ge, Yue Chen, Zhibin Hu, Hui Mao, Qiong Xu, Qing Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.934044/full
_version_ 1828195659628412928
author Yunfen Ge
Yue Chen
Zhibin Hu
Hui Mao
Qiong Xu
Qing Wu
author_facet Yunfen Ge
Yue Chen
Zhibin Hu
Hui Mao
Qiong Xu
Qing Wu
author_sort Yunfen Ge
collection DOAJ
description AimsTo evaluate the clinical efficiency of on-table extubation (OTE) versus delayed extubation in patients aged over 60 years that underwent minimally invasive mitral or aortic valve replacement surgery and evaluate the factors associated with successful OTE implementation.MaterialsPatients over 60 years with mitral or aortic valve disease who received minimally invasive mitral or aortic valve replacement surgery from October 2020 to October 2021 were selected retrospectively. We divided patients into the on-table extubated (OTE) group (n = 71) and the delayed extubation (DE) group (n = 22). Preoperative, intraoperative, and postoperative clinical variables were compared between the two groups.ResultsPatients in the DE group underwent longer surgery time, longer aortic occlusion clamping time and longer cardiopulmonary bypass time than those in the OTE group(217.48 ± 27.83 vs 275.91 ± 77.22, p = 0.002; 76.49 ± 16.00 vs 126.55 ± 54.85, p = 0.001; 112.87 ± 18.91 vs 160.77 ± 52.17, p = 0.001). Patients in the OTE group had shorter postoperative mechanical ventilation time (min), shorter ICU time, shorter postoperative hospital length of stay and lower total cost and medication cost (p < 0.05). The AUC for aortic occlusion clamping time was 0.81 (p < 0.01), making it the most significant predictor of on-table extubation success.ConclusionsOn-table extubation following mitral or aortic valve cardiac surgery was associated with a superior clinical outcome and high cost-effectiveness.
first_indexed 2024-04-12T09:47:21Z
format Article
id doaj.art-27a26d2e39f94febbe396d7cd8a37117
institution Directory Open Access Journal
issn 2296-875X
language English
last_indexed 2024-04-12T09:47:21Z
publishDate 2022-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Surgery
spelling doaj.art-27a26d2e39f94febbe396d7cd8a371172022-12-22T03:37:54ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-06-01910.3389/fsurg.2022.934044934044Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement SurgeryYunfen Ge0Yue Chen1Zhibin Hu2Hui Mao3Qiong Xu4Qing Wu5Center for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaHeart Center, Department of Cardiovascular Surgery, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaCenter for Reproductive Medicine, Department of Gynecology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, ChinaAimsTo evaluate the clinical efficiency of on-table extubation (OTE) versus delayed extubation in patients aged over 60 years that underwent minimally invasive mitral or aortic valve replacement surgery and evaluate the factors associated with successful OTE implementation.MaterialsPatients over 60 years with mitral or aortic valve disease who received minimally invasive mitral or aortic valve replacement surgery from October 2020 to October 2021 were selected retrospectively. We divided patients into the on-table extubated (OTE) group (n = 71) and the delayed extubation (DE) group (n = 22). Preoperative, intraoperative, and postoperative clinical variables were compared between the two groups.ResultsPatients in the DE group underwent longer surgery time, longer aortic occlusion clamping time and longer cardiopulmonary bypass time than those in the OTE group(217.48 ± 27.83 vs 275.91 ± 77.22, p = 0.002; 76.49 ± 16.00 vs 126.55 ± 54.85, p = 0.001; 112.87 ± 18.91 vs 160.77 ± 52.17, p = 0.001). Patients in the OTE group had shorter postoperative mechanical ventilation time (min), shorter ICU time, shorter postoperative hospital length of stay and lower total cost and medication cost (p < 0.05). The AUC for aortic occlusion clamping time was 0.81 (p < 0.01), making it the most significant predictor of on-table extubation success.ConclusionsOn-table extubation following mitral or aortic valve cardiac surgery was associated with a superior clinical outcome and high cost-effectiveness.https://www.frontiersin.org/articles/10.3389/fsurg.2022.934044/fullmitral or aortic valve diseaseon-table extubationdelayed extubationaortic occlusion clampingcardiopulmonary bypass time
spellingShingle Yunfen Ge
Yue Chen
Zhibin Hu
Hui Mao
Qiong Xu
Qing Wu
Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
Frontiers in Surgery
mitral or aortic valve disease
on-table extubation
delayed extubation
aortic occlusion clamping
cardiopulmonary bypass time
title Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
title_full Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
title_fullStr Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
title_full_unstemmed Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
title_short Clinical Evaluation of on-Table Extubation in Patients Aged Over 60 Years Undergoing Minimally Invasive Mitral or Aortic Valve Replacement Surgery
title_sort clinical evaluation of on table extubation in patients aged over 60 years undergoing minimally invasive mitral or aortic valve replacement surgery
topic mitral or aortic valve disease
on-table extubation
delayed extubation
aortic occlusion clamping
cardiopulmonary bypass time
url https://www.frontiersin.org/articles/10.3389/fsurg.2022.934044/full
work_keys_str_mv AT yunfenge clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery
AT yuechen clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery
AT zhibinhu clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery
AT huimao clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery
AT qiongxu clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery
AT qingwu clinicalevaluationofontableextubationinpatientsagedover60yearsundergoingminimallyinvasivemitraloraorticvalvereplacementsurgery