Effect of atorvastatin and rosuvastatin on the PCSK9 blood concentration in statin-naive patients with atherosclerosis
Statins are currently the main group of lipid-lowering drugs used in clinical practice. However not all patients manage to achieve ‘target’ levels of LDL. A possible cause is statin-induced increase of expression of hepatocyte PCSK9 which regulates LDL uptake.Aim. The aim of the study was to determi...
Main Authors: | A. Yu. Filatova, T. I. Arefieva, E. A. Klesareva, O. I. Afanasieva |
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Format: | Article |
Language: | Russian |
Published: |
«FIRMA «SILICEA» LLC
2019-06-01
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Series: | Российский кардиологический журнал |
Subjects: | |
Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3269 |
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