Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso
The canine transmissible venereal tumor is a type of round cell cancer that have the particularity of implanting in mucous tissue, when they lose their integrity, at which point the tumour proliferates and may even develop metastases. The tumor typically responds well to vincristine sulfate chemothe...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Spanish |
| Published: |
Universidad Nacional de Colombia
2019-01-01
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| Series: | Revista de la Facultad de Medicina Veterinaria y de Zootecnia |
| Subjects: | |
| Online Access: | http://www.redalyc.org/articulo.oa?id=407663035006 |
| _version_ | 1797249945150947328 |
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| author | A. P. Duzanski A. D. Ortiz H. B. Fêo M. W. Fonseca M. M. Flórez L. T Rodrigues F. Michelon N. S. Rocha |
| author_facet | A. P. Duzanski A. D. Ortiz H. B. Fêo M. W. Fonseca M. M. Flórez L. T Rodrigues F. Michelon N. S. Rocha |
| author_sort | A. P. Duzanski |
| collection | DOAJ |
| description | The canine transmissible venereal tumor is a type of round cell cancer that have the particularity of implanting in mucous tissue, when they lose their integrity, at which point the tumour proliferates and may even develop metastases. The tumor typically responds well to vincristine sulfate chemotherapy, although there are cases of resistance to the drug correlated with the tumoral phenotype. We describe herein a genital mixed TVTC case with metastases at spleen and failure at vincristine sulfate chemotherapeutic treatment in a five years old Australian Cattle Dog female. After the cytological, histological and cytogenetic diagnostic, the primary tumor was still characterized in progression phase and showed low major histocompatibility complex expression MHC (4,4 ± 2% class I e 11 ± 4,1% class II. The dog underwent therapeutic splenectomy and ovariohysterectomy and did not present tumor recurrence within 12 months of clinical follow-up. |
| first_indexed | 2024-03-07T20:18:19Z |
| format | Article |
| id | doaj.art-27a783b70e23457b989d1bf18d8eb724 |
| institution | Directory Open Access Journal |
| issn | 0120-2952 2357-3813 |
| language | Spanish |
| last_indexed | 2024-04-24T20:38:32Z |
| publishDate | 2019-01-01 |
| publisher | Universidad Nacional de Colombia |
| record_format | Article |
| series | Revista de la Facultad de Medicina Veterinaria y de Zootecnia |
| spelling | doaj.art-27a783b70e23457b989d1bf18d8eb7242024-03-21T19:37:25ZspaUniversidad Nacional de ColombiaRevista de la Facultad de Medicina Veterinaria y de Zootecnia0120-29522357-38132019-01-0166326027110.15446/rfmvz.v66n3.84262Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de casoA. P. DuzanskiA. D. OrtizH. B. FêoM. W. FonsecaM. M. FlórezL. T RodriguesF. MichelonN. S. RochaThe canine transmissible venereal tumor is a type of round cell cancer that have the particularity of implanting in mucous tissue, when they lose their integrity, at which point the tumour proliferates and may even develop metastases. The tumor typically responds well to vincristine sulfate chemotherapy, although there are cases of resistance to the drug correlated with the tumoral phenotype. We describe herein a genital mixed TVTC case with metastases at spleen and failure at vincristine sulfate chemotherapeutic treatment in a five years old Australian Cattle Dog female. After the cytological, histological and cytogenetic diagnostic, the primary tumor was still characterized in progression phase and showed low major histocompatibility complex expression MHC (4,4 ± 2% class I e 11 ± 4,1% class II. The dog underwent therapeutic splenectomy and ovariohysterectomy and did not present tumor recurrence within 12 months of clinical follow-up.http://www.redalyc.org/articulo.oa?id=407663035006tvtcdogmetastasischemotherapy |
| spellingShingle | A. P. Duzanski A. D. Ortiz H. B. Fêo M. W. Fonseca M. M. Flórez L. T Rodrigues F. Michelon N. S. Rocha Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso Revista de la Facultad de Medicina Veterinaria y de Zootecnia tvtc dog metastasis chemotherapy |
| title | Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso |
| title_full | Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso |
| title_fullStr | Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso |
| title_full_unstemmed | Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso |
| title_short | Tumor venéreo transmissível canino com resistência quimioterápica e metástase esplênica. Relato de caso |
| title_sort | tumor venereo transmissivel canino com resistencia quimioterapica e metastase esplenica relato de caso |
| topic | tvtc dog metastasis chemotherapy |
| url | http://www.redalyc.org/articulo.oa?id=407663035006 |
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