Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels

Chitosan is widely used in the production of various hydrogels due to its non-biological toxicity, good biocompatibility, and strong biodegradability. However, chitosan-based hydrogels have not been widely used in tissue engineering due to their poor mechanical strength, poor stability and high biot...

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Main Authors: Runing Liang, Dan Zhang, Junwei Guo, Shaohuang Bian, Cheng Yang, Lusi A, Weiwei Zhang, Feng Huang
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/25/4/2418
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author Runing Liang
Dan Zhang
Junwei Guo
Shaohuang Bian
Cheng Yang
Lusi A
Weiwei Zhang
Feng Huang
author_facet Runing Liang
Dan Zhang
Junwei Guo
Shaohuang Bian
Cheng Yang
Lusi A
Weiwei Zhang
Feng Huang
author_sort Runing Liang
collection DOAJ
description Chitosan is widely used in the production of various hydrogels due to its non-biological toxicity, good biocompatibility, and strong biodegradability. However, chitosan-based hydrogels have not been widely used in tissue engineering due to their poor mechanical strength, poor stability and high biotoxicity of cross-linking agents. As a green technology, low temperature plasma is rich in active groups that can be involved in various chemical reactions, such as replacing the components on the chitosan chain, contributing to the cross-linking of chitosan. In this study, a plasma-assisted preparation method of chitosan-based hydrogels was developed and the properties, including mechanics, water absorption, and degradation (or stability), were characterized and analyzed. It is proved that plasma treatment plays a significant role in improving the mechanical strength and stability of hydrogels.
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spelling doaj.art-27a87e6c6ecb4e209723d54d8bf7ee692024-02-23T15:20:55ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672024-02-01254241810.3390/ijms25042418Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based HydrogelsRuning Liang0Dan Zhang1Junwei Guo2Shaohuang Bian3Cheng Yang4Lusi A5Weiwei Zhang6Feng Huang7College of Science, China Agricultural University, Beijing 100083, ChinaCollege of Science, China Agricultural University, Beijing 100083, ChinaCollege of Science, China Agricultural University, Beijing 100083, ChinaCollege of Information and Electrical Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Science, China Agricultural University, Beijing 100083, ChinaCollege of Information and Electrical Engineering, China Agricultural University, Beijing 100083, ChinaCollege of Science, China Agricultural University, Beijing 100083, ChinaCollege of Science, China Agricultural University, Beijing 100083, ChinaChitosan is widely used in the production of various hydrogels due to its non-biological toxicity, good biocompatibility, and strong biodegradability. However, chitosan-based hydrogels have not been widely used in tissue engineering due to their poor mechanical strength, poor stability and high biotoxicity of cross-linking agents. As a green technology, low temperature plasma is rich in active groups that can be involved in various chemical reactions, such as replacing the components on the chitosan chain, contributing to the cross-linking of chitosan. In this study, a plasma-assisted preparation method of chitosan-based hydrogels was developed and the properties, including mechanics, water absorption, and degradation (or stability), were characterized and analyzed. It is proved that plasma treatment plays a significant role in improving the mechanical strength and stability of hydrogels.https://www.mdpi.com/1422-0067/25/4/2418low temperature plasmadielectric barrier dischargechitosan-based hydrogelspreparationcharacteristics
spellingShingle Runing Liang
Dan Zhang
Junwei Guo
Shaohuang Bian
Cheng Yang
Lusi A
Weiwei Zhang
Feng Huang
Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
International Journal of Molecular Sciences
low temperature plasma
dielectric barrier discharge
chitosan-based hydrogels
preparation
characteristics
title Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
title_full Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
title_fullStr Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
title_full_unstemmed Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
title_short Dielectric Barrier Discharge Plasma-Assisted Preparation of Chitosan-Based Hydrogels
title_sort dielectric barrier discharge plasma assisted preparation of chitosan based hydrogels
topic low temperature plasma
dielectric barrier discharge
chitosan-based hydrogels
preparation
characteristics
url https://www.mdpi.com/1422-0067/25/4/2418
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AT shaohuangbian dielectricbarrierdischargeplasmaassistedpreparationofchitosanbasedhydrogels
AT chengyang dielectricbarrierdischargeplasmaassistedpreparationofchitosanbasedhydrogels
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