Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit
Abstract Patients with hematological malignancy experience physical and psychological pain, such as a sense of isolation and confinement due to intensive chemotherapy in a protective isolation unit (PIU). We examined whether the intervention of a robotic puppy, aibo (manufactured by Sony), could imp...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-02-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-54286-4 |
| _version_ | 1827327950899380224 |
|---|---|
| author | Akiko Yamada Daigo Akahane Shiho Takeuchi Kaori Miyata Takako Sato Akihiko Gotoh |
| author_facet | Akiko Yamada Daigo Akahane Shiho Takeuchi Kaori Miyata Takako Sato Akihiko Gotoh |
| author_sort | Akiko Yamada |
| collection | DOAJ |
| description | Abstract Patients with hematological malignancy experience physical and psychological pain, such as a sense of isolation and confinement due to intensive chemotherapy in a protective isolation unit (PIU). We examined whether the intervention of a robotic puppy, aibo (manufactured by Sony), could improve patients' mental health as an alternative therapy for pet therapy, which is not feasible in PIU. This study included 21 patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) (n = 16) or autologous HSCT (n = 5). The patients were randomly divided into the aibo and control groups. Psychological effects were regularly assessed by measuring the levels of salivary stress hormone chromogranin A (CgA), serum oxytocin, and serum cortisol and the quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR) scores. The aibo group demonstrated a significant decrease in CgA level, while the control group showed the opposite trend. In addition, changes in serum oxytocin and cortisol levels indicated that aibo helped reduce stress. There was no significant difference in the QIDS-SR scores between the two groups; however, the psychomotor activity in the aibo group improved significantly. These findings suggest that aibo intervention during a stay in a PIU can improve the mental health of patients with hematological malignancies who have undergone HSCT. |
| first_indexed | 2024-03-07T15:09:52Z |
| format | Article |
| id | doaj.art-27ac066418da4297a214b17614bf18f0 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-07T15:09:52Z |
| publishDate | 2024-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-27ac066418da4297a214b17614bf18f02024-03-05T18:42:03ZengNature PortfolioScientific Reports2045-23222024-02-0114111310.1038/s41598-024-54286-4Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unitAkiko Yamada0Daigo Akahane1Shiho Takeuchi2Kaori Miyata3Takako Sato4Akihiko Gotoh5Department of Hematology, Tokyo Medical UniversityDepartment of Hematology, Tokyo Medical UniversityCenter for Diversity, Tokyo Medical UniversityDepartment of Nursing, Tokyo Medical UniversityDepartment of Nursing, Tokyo Medical UniversityDepartment of Hematology, Tokyo Medical UniversityAbstract Patients with hematological malignancy experience physical and psychological pain, such as a sense of isolation and confinement due to intensive chemotherapy in a protective isolation unit (PIU). We examined whether the intervention of a robotic puppy, aibo (manufactured by Sony), could improve patients' mental health as an alternative therapy for pet therapy, which is not feasible in PIU. This study included 21 patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) (n = 16) or autologous HSCT (n = 5). The patients were randomly divided into the aibo and control groups. Psychological effects were regularly assessed by measuring the levels of salivary stress hormone chromogranin A (CgA), serum oxytocin, and serum cortisol and the quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR) scores. The aibo group demonstrated a significant decrease in CgA level, while the control group showed the opposite trend. In addition, changes in serum oxytocin and cortisol levels indicated that aibo helped reduce stress. There was no significant difference in the QIDS-SR scores between the two groups; however, the psychomotor activity in the aibo group improved significantly. These findings suggest that aibo intervention during a stay in a PIU can improve the mental health of patients with hematological malignancies who have undergone HSCT.https://doi.org/10.1038/s41598-024-54286-4Hematopoietic stem cell transplantationChromogranin APsychiatryQuality of lifeRobot therapy |
| spellingShingle | Akiko Yamada Daigo Akahane Shiho Takeuchi Kaori Miyata Takako Sato Akihiko Gotoh Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit Scientific Reports Hematopoietic stem cell transplantation Chromogranin A Psychiatry Quality of life Robot therapy |
| title | Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| title_full | Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| title_fullStr | Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| title_full_unstemmed | Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| title_short | Robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| title_sort | robot therapy aids mental health in patients with hematological malignancy during hematopoietic stem cell transplantation in a protective isolation unit |
| topic | Hematopoietic stem cell transplantation Chromogranin A Psychiatry Quality of life Robot therapy |
| url | https://doi.org/10.1038/s41598-024-54286-4 |
| work_keys_str_mv | AT akikoyamada robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit AT daigoakahane robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit AT shihotakeuchi robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit AT kaorimiyata robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit AT takakosato robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit AT akihikogotoh robottherapyaidsmentalhealthinpatientswithhematologicalmalignancyduringhematopoieticstemcelltransplantationinaprotectiveisolationunit |