Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction.

Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction.

A naturally-occurring fragment of tyrosyl-tRNA synthetase (TyrRS) has been shown in higher eukaryotes to 'moonlight' as a pro-angiogenic cytokine in addition to its primary role in protein translation. Pro-angiogenic cytokines have previously been proposed to be promising therapeutic mecha...

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Bibliographic Details
Main Authors: Margaret E McCormick, Mauricio Rojas, Tyler Moser-Katz, Ellie Tzima, John S Reader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4190278?pdf=render

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