Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection.

Local IL-17A potentiates early neutrophil recruitment to the respiratory tract during severe RSV infection.

Respiratory syncytial virus (RSV) bronchiolitis triggers a strong innate immune response characterized by excessive neutrophil infiltration which contributes to RSV induced pathology. The cytokine IL-17A enhances neutrophil infiltration into virus infected lungs. IL-17A is however best known as an e...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Arie Jan Stoppelenburg, Vahid Salimi, Marije Hennus, Maud Plantinga, Ron Huis in 't Veld, Jona Walk, Jenny Meerding, Frank Coenjaerts, Louis Bont, Marianne Boes
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24194936/pdf/?tool=EBI

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