MiR-326 inhibits trophoblast growth, migration, and invasion by targeting PAX8 via Hippo pathway

MiR-326 inhibits trophoblast growth, migration, and invasion by targeting PAX8 via Hippo pathway

Abstract Preeclampsia (PE), a pregnancy disorder that affects 5–7% of pregnant women, is among the primary causes for maternal and perinatal mortality. PE is believed to be associated with insufficient invasion of villous and extravillous trophoblasts (EVTs), which hampers uterine spiral artery remo...

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Bibliographic Details
Main Authors: Junjie Zang, Min Yan, Yan Zhang, Wei Peng, Jianxin Zuo, Huansheng Zhou, Guoqiang Gao, Min Li, Yijing Chu, Yuanhua Ye
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Reproductive Biology and Endocrinology
Subjects:
miR-326
PAX8
Trophoblasts
Hippo signaling
Online Access:https://doi.org/10.1186/s12958-022-00909-2

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