Development of a Dual Drug-Loaded, Surfactant-Stabilized Contrast Agent Containing Oxygen

Development of a Dual Drug-Loaded, Surfactant-Stabilized Contrast Agent Containing Oxygen

Co-delivery of cancer therapeutics improves efficacy and encourages synergy, but delivery faces challenges, including multidrug resistance and spatiotemporal distribution of therapeutics. To address these, we added paclitaxel to previously developed acoustically labile, oxygen-core, surfactant-stabi...

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Bibliographic Details
Main Authors: Raj Patel, Quezia Lacerda, Brian E. Oeffinger, John R. Eisenbrey, Ankit K. Rochani, Gagan Kaushal, Corinne E. Wessner, Margaret A. Wheatley
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Polymers
Subjects:
ultrasound contrast agent
microbubbles
theranostic agents
ultrasound-triggered drug delivery
dual drug loading
surfactant
Online Access:https://www.mdpi.com/2073-4360/14/8/1568

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