Repurposing Sitagliptin for COVID-19 in Adults: Clinical Benefits and An Approach for the Mechanism

Repurposing Sitagliptin for COVID-19 in Adults: Clinical Benefits and An Approach for the Mechanism

Introduction: Dipeptidyl peptidase-4 (DPP4) has been shown to be a functional receptor for MERS-CoV. An interaction between the viral spike protein and DPP4 is thought to facilitate viral entry. We aimed to find out whether sitagliptin, a member of DPP4 inhibitors, would have beneficial effects in C...

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Bibliographic Details
Main Authors: Güle ÇINAR, Satı COŞGUN YAZGAN, Atilla Halil ELHAN, İrem AKDEMİR KALKAN, Ezgi GÜLTEN, Mehmet Altay ÜNAL, Özgür DEMİR, Kemal Osman MEMİKOĞLU, Mehmet Serhat BİRENGEL, Zeynep Ceren KARAHAN, Hasan NAZIR, Ebru EVREN, Alpay AZAP
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2022-06-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
covid-19
dpp4 inhibitors
ace2
sitagliptin
sars-cov-2
Online Access:http://floradergisi.org/managete/fu_folder/2022-02/324-334%20Gule%20Cinar.pdf

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http://floradergisi.org/managete/fu_folder/2022-02/324-334%20Gule%20Cinar.pdf

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