Farnesylthiosalicylic acid-derivatized PEI-based nanocomplex for improved tumor vaccination

Farnesylthiosalicylic acid-derivatized PEI-based nanocomplex for improved tumor vaccination

Cancer vaccines that make use of tumor antigens represent a promising therapeutic strategy by stimulating immune responses against tumors to generate long-term anti-tumor immunity. However, vaccines have shown limited clinical efficacy due to inefficient delivery. In this study, we focus on vaccine...

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Bibliographic Details
Main Authors: Yuang Chen, Yixian Huang, Haozhe Huang, Zhangyi Luo, Ziqian Zhang, Runzi Sun, Zhuoya Wan, Jingjing Sun, Binfeng Lu, Song Li
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
farnesylthiosalicylic acid
polyethylenimine
nanocomplex
vaccination
neoantigen
immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121002353

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