Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype
Abstract Background Renal cell carcinomas (RCC) are characterized by the deregulation of several hundred hyperosmolality-responsive genes. High expression of a subset of these genes including the Ran binding protein 3 like (RANBP3L) is linked to a favorable prognostic outcome in RCC. However, the ce...
Main Authors: | Dmitry Chernyakov, Alexander Groß, Annika Fischer, Nicola Bornkessel, Christoph Schultheiss, Dennis Gerloff, Bayram Edemir |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-07-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-021-01982-y |
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