In vitro bactericidal activity of 3-cinnamoyl-4-hydroxy-6-methyl-2-pyrone (CHP) against drug-susceptible, drug-resistant and drug-tolerant isolates of Mycobacterium tuberculosis

In vitro bactericidal activity of 3-cinnamoyl-4-hydroxy-6-methyl-2-pyrone (CHP) against drug-susceptible, drug-resistant and drug-tolerant isolates of Mycobacterium tuberculosis

Objectives: Tuberculosis (TB) poses a serious global threat to humans. New bactericidal agents that can shorten treatment duration and target drug resistance still remain a top priority in the discovery of anti-TB drugs. The objective of this study was to investigate the bactericidal potential of 3-...

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Bibliographic Details
Main Authors: Zubair Shanib Bhat, Muzafar Ahmad Rather, Hafiz Ul Lah, Aehtesham Hussain, Mubashir Maqbool, Syed Khalid Yousuf, Zuhra Jabeen, Mushtaq Ahmad Wani, Zahoor Ahmad
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antituberculosis activity
Mycobacterium tuberculosis
MDR-TB
Dormant/tolerant bacilli
Cinnamoyl pyrones
Synergism
Online Access:http://www.sciencedirect.com/science/article/pii/S221371651930311X

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