Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice
Alzheimer’s disease (AD) is the most common neurodegenerative disease. Most cases of AD are considered idiopathic and likely due to a combination of genetic, environmental, and lifestyle-related risk factors. Despite occurring decades before the typical age of an AD diagnosis, early-life stress (ELS...
Main Authors: | M.G. Garcia, A. Paulus, S. Vázquez-Reyes, O. Klementieva, G.K. Gouras, S. Bachiller, T. Deierborg |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-10-01
|
Series: | Brain, Behavior, & Immunity - Health |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666354623000777 |
Similar Items
-
Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
by: S. Bachiller, et al.
Published: (2022-06-01) -
Maternal separation leads to regional hippocampal microglial activation and alters the behavior in the adolescence in a sex-specific manner
by: S. Bachiller, et al.
Published: (2020-12-01) -
RETRACTED ARTICLE: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease
by: Panchanan Maiti, et al.
Published: (2018-02-01) -
Liraglutide Has Anti-Inflammatory and Anti-Amyloid Properties in Streptozotocin-Induced and 5xFAD Mouse Models of Alzheimer’s Disease
by: Leela Paladugu, et al.
Published: (2021-01-01) -
Dexmedetomidine exerts an anti-inflammatory effect via α2 adrenoceptors to alleviate cognitive dysfunction in 5xFAD mice
by: Su-mei Luo, et al.
Published: (2022-09-01)