Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review
BackgroundDermoscopy is a non-invasive adjuvant diagnostic tool that allows clinicians to visualize microscopic features of cutaneous disorders. Recent studies have demonstrated that dermoscopy can be used to diagnose onychomycosis. We performed this systematic review to identify the characteristic...
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Frontiers Media S.A.
2022-10-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1048913/full |
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| author | Sophie Soyeon Lim Laura Hui Jungyoon Ohn Jungyoon Ohn Youngjoo Cho Choon Chiat Oh Je-Ho Mun Je-Ho Mun |
| author_facet | Sophie Soyeon Lim Laura Hui Jungyoon Ohn Jungyoon Ohn Youngjoo Cho Choon Chiat Oh Je-Ho Mun Je-Ho Mun |
| author_sort | Sophie Soyeon Lim |
| collection | DOAJ |
| description | BackgroundDermoscopy is a non-invasive adjuvant diagnostic tool that allows clinicians to visualize microscopic features of cutaneous disorders. Recent studies have demonstrated that dermoscopy can be used to diagnose onychomycosis. We performed this systematic review to identify the characteristic dermoscopic features of onychomycosis and understand their diagnostic utility.MethodsWe searched the Medline, Embase, Scopus, and Cochrane databases from conception until May 2021. Studies on the dermoscopic features of onychomycosis were screened. The exclusion criteria were as follows: fewer than 5 cases of onychomycosis, review articles, and studies including onychomycosis cases that were not mycologically verified. Studies on fungal melanonychia were analyzed separately. We adhered to the MOOSE guidelines. Independent data extraction was performed. Data were pooled using a random effects model to account for study heterogeneity. The primary outcome was the diagnostic accuracy of the dermoscopic features of onychomycosis. This was determined by pooling the sensitivity and specificity values of the dermoscopic features identified during the systematic review using the DerSimonian-Laird method. Meta-DiSc version 1.4 and Review Manager 5.4.1 were used to calculate these values.ResultsWe analyzed 19 articles on 1693 cases of onychomycosis and 5 articles on 148 cases of fungal melanonychia. Commonly reported dermoscopic features of onychomycosis were spikes or spiked pattern (509, 30.1%), jagged or spiked edges or jagged edge with spikes (188, 11.1%), jagged proximal edge (175, 10.3%), subungual hyperkeratosis (131, 7.7%), ruins appearance, aspect or pattern (573, 33.8%), and longitudinal striae (929, 54.9%). Commonly reported features of fungal melanonychia included multicolor (101, 68.2%), non-longitudinal homogenous pigmentation (75, 50.7%) and longitudinal white or yellow streaks (52, 31.5%).ConclusionThis study highlights the commonly identified dermoscopic features of onychomycosis. Recognizing such characteristic dermoscopic features of onychomycosis can assist clinicians diagnose onychomycosis by the bedside. |
| first_indexed | 2024-04-13T22:31:15Z |
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| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-13T22:31:15Z |
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| spelling | doaj.art-27c876a5c5fa4bcab4d03902702091e22022-12-22T02:26:54ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-10-01910.3389/fmed.2022.10489131048913Diagnostic accuracy of dermoscopy for onychomycosis: A systematic reviewSophie Soyeon Lim0Laura Hui1Jungyoon Ohn2Jungyoon Ohn3Youngjoo Cho4Choon Chiat Oh5Je-Ho Mun6Je-Ho Mun7Alfred Health, Melbourne, VIC, AustraliaDepartment of Dermatology, Singapore General Hospital, Singapore, SingaporeDepartment of Dermatology, Seoul National University College of Medicine, Seoul, South KoreaInstitute of Human-Environment Interface Biology, Seoul National University, Seoul, South KoreaDepartment of Applied Statistics, Konkuk University, Seoul, South KoreaDepartment of Dermatology, Singapore General Hospital, Singapore, SingaporeDepartment of Dermatology, Seoul National University College of Medicine, Seoul, South KoreaInstitute of Human-Environment Interface Biology, Seoul National University, Seoul, South KoreaBackgroundDermoscopy is a non-invasive adjuvant diagnostic tool that allows clinicians to visualize microscopic features of cutaneous disorders. Recent studies have demonstrated that dermoscopy can be used to diagnose onychomycosis. We performed this systematic review to identify the characteristic dermoscopic features of onychomycosis and understand their diagnostic utility.MethodsWe searched the Medline, Embase, Scopus, and Cochrane databases from conception until May 2021. Studies on the dermoscopic features of onychomycosis were screened. The exclusion criteria were as follows: fewer than 5 cases of onychomycosis, review articles, and studies including onychomycosis cases that were not mycologically verified. Studies on fungal melanonychia were analyzed separately. We adhered to the MOOSE guidelines. Independent data extraction was performed. Data were pooled using a random effects model to account for study heterogeneity. The primary outcome was the diagnostic accuracy of the dermoscopic features of onychomycosis. This was determined by pooling the sensitivity and specificity values of the dermoscopic features identified during the systematic review using the DerSimonian-Laird method. Meta-DiSc version 1.4 and Review Manager 5.4.1 were used to calculate these values.ResultsWe analyzed 19 articles on 1693 cases of onychomycosis and 5 articles on 148 cases of fungal melanonychia. Commonly reported dermoscopic features of onychomycosis were spikes or spiked pattern (509, 30.1%), jagged or spiked edges or jagged edge with spikes (188, 11.1%), jagged proximal edge (175, 10.3%), subungual hyperkeratosis (131, 7.7%), ruins appearance, aspect or pattern (573, 33.8%), and longitudinal striae (929, 54.9%). Commonly reported features of fungal melanonychia included multicolor (101, 68.2%), non-longitudinal homogenous pigmentation (75, 50.7%) and longitudinal white or yellow streaks (52, 31.5%).ConclusionThis study highlights the commonly identified dermoscopic features of onychomycosis. Recognizing such characteristic dermoscopic features of onychomycosis can assist clinicians diagnose onychomycosis by the bedside.https://www.frontiersin.org/articles/10.3389/fmed.2022.1048913/fullfungal nail infectiononychomycosisdermoscopyfungal melanonychiaonychoscopy |
| spellingShingle | Sophie Soyeon Lim Laura Hui Jungyoon Ohn Jungyoon Ohn Youngjoo Cho Choon Chiat Oh Je-Ho Mun Je-Ho Mun Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review Frontiers in Medicine fungal nail infection onychomycosis dermoscopy fungal melanonychia onychoscopy |
| title | Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review |
| title_full | Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review |
| title_fullStr | Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review |
| title_full_unstemmed | Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review |
| title_short | Diagnostic accuracy of dermoscopy for onychomycosis: A systematic review |
| title_sort | diagnostic accuracy of dermoscopy for onychomycosis a systematic review |
| topic | fungal nail infection onychomycosis dermoscopy fungal melanonychia onychoscopy |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1048913/full |
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