SHIP1 Activator AQX-1125 Regulates Osteogenesis and Osteoclastogenesis Through PI3K/Akt and NF-κb Signaling

SHIP1 Activator AQX-1125 Regulates Osteogenesis and Osteoclastogenesis Through PI3K/Akt and NF-κb Signaling

With the worldwide aging population, the prevalence of osteoporosis is on the rise, particularly the number of postmenopausal women with the condition. However, the various adverse side effects associated with the currently available treatment options underscore the need to develop novel therapies....

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Bibliographic Details
Main Authors: Xudong Xie, Liangcong Hu, Bobin Mi, Adriana C. Panayi, Hang Xue, Yiqiang Hu, Guodong Liu, Lang Chen, Chenchen Yan, Kangkang Zha, Ze Lin, Wu Zhou, Fei Gao, Guohui Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
AQX-1125
SHIP1
bone loss
osteoblast
osteoclast
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.826023/full

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